| Basic Information | |
|---|---|
| Species | Aquilegia coerulea |
| Cazyme ID | Aquca_013_00454.6 |
| Family | AA3 |
| Protein Properties | Length: 394 Molecular Weight: 42175.7 Isoelectric Point: 6.415 |
| Chromosome | Chromosome/Scaffold: 13 Start: 2907533 End: 2910881 |
| Description | Glucose-methanol-choline (GMC) oxidoreductase family protein |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| AA3 | 37 | 332 | 0 |
| DSTSAPNISYYDYIIIGGGTAGCPLAATLSQNYSVLLIERGGSPYGNPNITNLANFGASLSDNTPTSPAQPFISEDGVYNSRARVLGGGSCLNAGFYTRA SVDYVNNAGWDGNLVNQSYQWVEKLVAFEPPMRQWQSAVRDGLLEVGVTPYNGFTYDHIIGTKVGGTIFDRDGHRHTAADLLEYANPKGLTVLLNATVHQ ILFRTKGKAKPTAHGVIFSDSLGIKHRAQLNKGSKNEIILSAGALGSPQLLMLSGVGPAEHLRSHNITVLVDQPMVGQGMSDNPMNAIYIPSPLDV | |||
| Full Sequence |
|---|
| Protein Sequence Length: 394 Download |
| MDLSWCRFVG ALVVAILLCL QGFCYSEQAP NYSFVHDSTS APNISYYDYI IIGGGTAGCP 60 LAATLSQNYS VLLIERGGSP YGNPNITNLA NFGASLSDNT PTSPAQPFIS EDGVYNSRAR 120 VLGGGSCLNA GFYTRASVDY VNNAGWDGNL VNQSYQWVEK LVAFEPPMRQ WQSAVRDGLL 180 EVGVTPYNGF TYDHIIGTKV GGTIFDRDGH RHTAADLLEY ANPKGLTVLL NATVHQILFR 240 TKGKAKPTAH GVIFSDSLGI KHRAQLNKGS KNEIILSAGA LGSPQLLMLS GVGPAEHLRS 300 HNITVLVDQP MVGQGMSDNP MNAIYIPSPL DVEVSLIQVV GITPVGSYIE AASGANFGSP 360 AGMQSFGMFE PQENSSLYVP IKVTQAWRSF SKQ* |
| Functional Domains Download unfiltered results here | ||||||
|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description |
| PRK02106 | PRK02106 | 8.0e-20 | 205 | 318 | 122 | + choline dehydrogenase; Validated |
| TIGR01810 | betA | 2.0e-20 | 56 | 319 | 304 | + choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli , Staphylococcus xylosus , and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified [Cellular processes, Adaptations to atypical conditions]. |
| TIGR03970 | Rv0697 | 5.0e-21 | 56 | 320 | 303 | + dehydrogenase, Rv0697 family. This model describes a set of dehydrogenases belonging to the glucose-methanol-choline oxidoreductase (GMC oxidoreductase) family. Members of the present family are restricted to Actinobacterial genome contexts containing also members of families TIGR03962 and TIGR03969 (the mycofactocin system), and are proposed to be uniform in function. |
| COG2303 | BetA | 2.0e-22 | 57 | 343 | 330 | + Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism] |
| PLN02785 | PLN02785 | 5.0e-154 | 56 | 358 | 303 | + Protein HOTHEAD |
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors |
| GO:0050660 | flavin adenine dinucleotide binding |
| GO:0055114 | oxidation-reduction process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI34759.1 | 0 | 21 | 392 | 21 | 398 | unnamed protein product [Vitis vinifera] |
| RefSeq | XP_002282510.1 | 0 | 35 | 392 | 1 | 364 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002298074.1 | 0 | 1 | 382 | 1 | 380 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002509694.1 | 0 | 3 | 382 | 6 | 387 | glucose-methanol-choline (gmc) oxidoreductase, putative [Ricinus communis] |
| RefSeq | XP_002510860.1 | 0 | 4 | 376 | 5 | 377 | glucose-methanol-choline (gmc) oxidoreductase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3gdp_B | 0 | 33 | 343 | 13 | 322 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
| PDB | 3gdp_A | 0 | 33 | 343 | 13 | 322 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
| PDB | 3gdn_B | 0 | 33 | 343 | 13 | 322 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
| PDB | 3gdn_A | 0 | 33 | 343 | 13 | 322 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
| PDB | 1ju2_B | 0 | 33 | 343 | 13 | 322 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
