Basic Information | |
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Species | Aquilegia coerulea |
Cazyme ID | Aquca_013_00507.1 |
Family | GH29 |
Protein Properties | Length: 486 Molecular Weight: 55185.6 Isoelectric Point: 7.2947 |
Chromosome | Chromosome/Scaffold: 13 Start: 3343878 End: 3345806 |
Description | alpha-L-fucosidase 1 |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GH29 | 38 | 340 | 0 |
PSASQLKWQQREVIMFMHFGVNTFTDSEWGTGHEDPAIFNPTALNANQWVDTAIKAGISLMILTAKHHDGFCLWPSKYTDHSVISSPWRDGKGDVVREFV DAAKVRGVDIGLYLSPWDRHEKRYGKEISYNEYYLGQLQELLKRYGSVQEIWFDGAKGSDAPNMSYYFSDWFSMVKELQGSINIFSDAGLDVRWVGNEKG YAGNTCWSTINRTSLTIGSSAESYLNQGDPRGTDWLPPECDVSIRTGWFWHKSQKPKPLSHLLNIYYKSVGRNCVLLLNVPPNTTGLISETDVQRLGEFH KAI |
Full Sequence |
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Protein Sequence Length: 486 Download |
MAVFWSFWFM LTLLETFKFP VSSWKPATTP PLPILPLPSA SQLKWQQREV IMFMHFGVNT 60 FTDSEWGTGH EDPAIFNPTA LNANQWVDTA IKAGISLMIL TAKHHDGFCL WPSKYTDHSV 120 ISSPWRDGKG DVVREFVDAA KVRGVDIGLY LSPWDRHEKR YGKEISYNEY YLGQLQELLK 180 RYGSVQEIWF DGAKGSDAPN MSYYFSDWFS MVKELQGSIN IFSDAGLDVR WVGNEKGYAG 240 NTCWSTINRT SLTIGSSAES YLNQGDPRGT DWLPPECDVS IRTGWFWHKS QKPKPLSHLL 300 NIYYKSVGRN CVLLLNVPPN TTGLISETDV QRLGEFHKAI NTIFSVNYAE GCTIKASSQR 360 GSMSDEFGPE KVIDEDHLWS YWAPEDNSNH EHWIELDGKE KILKFNVVRI QEAIGLGQRI 420 KHHKVYADGK LIASGTTIGY KRLHRLDDGV IYAQRVRIVI KESRGLPLIS SIGLHFDPFR 480 HPKGT* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam01120 | Alpha_L_fucos | 7.0e-28 | 52 | 338 | 324 | + Alpha-L-fucosidase. | ||
smart00812 | Alpha_L_fucos | 1.0e-29 | 52 | 336 | 325 | + Alpha-L-fucosidase. O-Glycosyl hydrolases (EC 3.2.1.-) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site. Because the fold of proteins is better conserved than their sequences, some of the families can be grouped in 'clans'. Family 29 encompasses alpha-L-fucosidases, which is a lysosomal enzyme responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. Deficiency of alpha-L-fucosidase results in the lysosomal storage disease fucosidosis. | ||
COG3669 | COG3669 | 1.0e-63 | 42 | 474 | 447 | + Alpha-L-fucosidase [Carbohydrate transport and metabolism] |
Gene Ontology | |
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GO Term | Description |
GO:0004560 | alpha-L-fucosidase activity |
GO:0005975 | carbohydrate metabolic process |
GO:0007155 | cell adhesion |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | XP_002270630.1 | 0 | 40 | 482 | 21 | 462 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002270674.1 | 0 | 27 | 485 | 5 | 464 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002318264.1 | 0 | 1 | 485 | 1 | 485 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002322431.1 | 0 | 1 | 482 | 1 | 483 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002510887.1 | 0 | 1 | 482 | 1 | 483 | alpha-l-fucosidase, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3eyp_B | 0 | 33 | 475 | 5 | 454 | A Chain A, Crystal Structure Of Putative Alpha-L-Fucosidase From Bacteroides Thetaiotaomicron |
PDB | 3eyp_A | 0 | 33 | 475 | 5 | 454 | A Chain A, Crystal Structure Of Putative Alpha-L-Fucosidase From Bacteroides Thetaiotaomicron |
PDB | 3ues_B | 0 | 38 | 470 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis Complexed With Deoxyfuconojirimycin |
PDB | 3ues_A | 0 | 38 | 470 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis Complexed With Deoxyfuconojirimycin |
PDB | 3mo4_B | 0 | 38 | 470 | 21 | 473 | A Chain A, The Crystal Structure Of An Alpha-(1-3,4)-Fucosidase From Bifidobacterium Longum Subsp. Infantis Atcc 15697 |