Basic Information | |
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Species | Aquilegia coerulea |
Cazyme ID | Aquca_013_00701.1 |
Family | GT47 |
Protein Properties | Length: 446 Molecular Weight: 51571.5 Isoelectric Point: 6.8575 |
Chromosome | Chromosome/Scaffold: 13 Start: 4572951 End: 4574614 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 35 | 385 | 0 |
CTGKWIHIRKLPSRFNLDLLLNCSDYPLYEDFCPYLANHGLGHKTHNRSHSWYRTDPYMLELIFHRRILEYPCLTSNPIQANAIYLPYYAAIDAFRYFYG ADYNSSAQHGLHLYNFLQQDNSYIWNRNFGHDHFLVMARPAWDFSQPLGNDPPLWGTSFLQVPEFYNVTALTLEARPWPWQEQAIPYPTSFHPPSIALLE NWIERVRRGHRTTFMLFAGGGGLGSSPNIRRSIRDECENTTIISNRFIGSSFTDVCRIVDCSNGVCEHDPYRYMRPMLHASFCLQPPGDTPTRRSTFDAI LAGCIPVFFEESSAQTQFGWHLPEDQYEEFSVFIPKEEVVSKGLQIIDVLL |
Full Sequence |
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Protein Sequence Length: 446 Download |
MSIHFFFFFS VLFLLNINSV YSQQTGSDLD PEQECTGKWI HIRKLPSRFN LDLLLNCSDY 60 PLYEDFCPYL ANHGLGHKTH NRSHSWYRTD PYMLELIFHR RILEYPCLTS NPIQANAIYL 120 PYYAAIDAFR YFYGADYNSS AQHGLHLYNF LQQDNSYIWN RNFGHDHFLV MARPAWDFSQ 180 PLGNDPPLWG TSFLQVPEFY NVTALTLEAR PWPWQEQAIP YPTSFHPPSI ALLENWIERV 240 RRGHRTTFML FAGGGGLGSS PNIRRSIRDE CENTTIISNR FIGSSFTDVC RIVDCSNGVC 300 EHDPYRYMRP MLHASFCLQP PGDTPTRRST FDAILAGCIP VFFEESSAQT QFGWHLPEDQ 360 YEEFSVFIPK EEVVSKGLQI IDVLLGIPKA QVRRMREKVI ELMPRVVYRR HGGSMEWRGV 420 KDAFDLAVEG TIDRIKSRVA TRNSS* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 9.0e-55 | 35 | 375 | 356 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_193989.1 | 0 | 20 | 439 | 25 | 435 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002267390.1 | 0 | 27 | 439 | 24 | 438 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002304426.1 | 0 | 15 | 439 | 12 | 429 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002329867.1 | 0 | 7 | 443 | 8 | 436 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002529790.1 | 0 | 2 | 439 | 4 | 449 | catalytic, putative [Ricinus communis] |