| Basic Information | |
|---|---|
| Species | Aquilegia coerulea |
| Cazyme ID | Aquca_013_00900.2 |
| Family | GT68 |
| Protein Properties | Length: 574 Molecular Weight: 66244.1 Isoelectric Point: 7.4501 |
| Chromosome | Chromosome/Scaffold: 13 Start: 5929685 End: 5933507 |
| Description | O-fucosyltransferase family protein |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT68 | 255 | 548 | 0 |
| NRVLVIPSSKVDYQYDRILDIDHINQCFGRKVVISFEEFSQIKKKNMRIDRFICYVSLPQPCYVDEEHAKRLKALGVSIPKLEPAWVEDVKEPKNRTVKD VMEKFSSNDEVLAIGDLFYADVEKEWISQPGGPLSHKCKTLIEPSRLIMVTAQRFIQTFLGKNFIALHFRRHGFLKFCNAKTQSCFFPIPQAANCITRVA ERANTPVIYLSTDAAESETDLLQSLTMLNGRPIPLVKRPARNSAEKWDALLYRHNIEGDSQVEAMLDKTICAMSSVFIGSSGSTFTEDIFRLRK | |||
| Full Sequence |
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| Protein Sequence Length: 574 Download |
| MMDRETTSSS DEEDDRENLI EQNERKQQLH RSTFEIASEI KTKISRNFNF NKRYCLFAIC 60 LPLFLFLIFF SFDVRSLFTS VSTMKKIDSS PIDKMREAEL KALYLLKEQQ FELFHVWNRS 120 LSDARLSNLN DTEVLNVNST VKLNSTVEIN NHVLKMTMED FRSVVLKQIR LNKEIQQALL 180 SSHRVGNMSE LVNDNVDERF VGYSGCKKVD HVGEKKRIEW KPKSNKYLFA ICLSGQMSNH 240 LICLEKHMFF AALLNRVLVI PSSKVDYQYD RILDIDHINQ CFGRKVVISF EEFSQIKKKN 300 MRIDRFICYV SLPQPCYVDE EHAKRLKALG VSIPKLEPAW VEDVKEPKNR TVKDVMEKFS 360 SNDEVLAIGD LFYADVEKEW ISQPGGPLSH KCKTLIEPSR LIMVTAQRFI QTFLGKNFIA 420 LHFRRHGFLK FCNAKTQSCF FPIPQAANCI TRVAERANTP VIYLSTDAAE SETDLLQSLT 480 MLNGRPIPLV KRPARNSAEK WDALLYRHNI EGDSQVEAML DKTICAMSSV FIGSSGSTFT 540 EDIFRLRKDW QTASVCDEYL CQDEQPNFIA ENE* 600 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam10250 | O-FucT | 0.0004 | 250 | 540 | 320 | + GDP-fucose protein O-fucosyltransferase. This is a family of conserved proteins representing the enzyme responsible for adding O-fucose to EGF (epidermal growth factor-like) repeats. Six highly conserved cysteines are present in O-FucT-1 as well as a DXD-like motif (ERD), conserved in mammals, Drosophila, and C. elegans. Both features are characteristic of several glycosyltransferase families. The enzyme is a membrane-bound protein released by proteolysis and, as for most glycosyltransferases, is strongly activated by manganese. | ||
| cd11548 | NodZ_like | 0.0003 | 393 | 541 | 152 | + Alpha 1,6-fucosyltransferase similar to Bradyrhizobium NodZ. Bradyrhizobium NodZ is an alpha 1,6-fucosyltransferase involved in the biosynthesis of the nodulation factor, a lipo-chitooligosaccharide formed by three-to-six beta-1,4-linked N-acetyl-d-glucosamine (GlcNAc) residues and a fatty acid acyl group attached to the nitrogen atom at the non-reducing end. NodZ transfers L-fucose from the GDP-beta-L-fucose donor to the reducing residue of the chitin oligosaccharide backbone, before the attachment of a fatty acid group. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. | ||
| cd11296 | O-FucT_like | 3.0e-5 | 227 | 270 | 44 | + GDP-fucose protein O-fucosyltransferase and related proteins. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. | ||
| cd11298 | O-FucT-2 | 4.0e-8 | 400 | 549 | 150 | + GDP-fucose protein O-fucosyltransferase 2. O-FucT-2 adds O-fucose to thrombospondin type 1 repeats (TSRs), and appears conserved in bilateria. The O-fucosylation of TSRs appears to play a role in regulating secretion of metalloproteases of the ADAMTS superfamily. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. | ||
| cd11296 | O-FucT_like | 4.0e-16 | 390 | 547 | 168 | + GDP-fucose protein O-fucosyltransferase and related proteins. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAD50008.1 | 0 | 8 | 573 | 4 | 594 | AC007651_3 Hypothetical Protein [Arabidopsis thaliana] |
| RefSeq | NP_173170.2 | 0 | 8 | 573 | 4 | 564 | unknown protein [Arabidopsis thaliana] |
| RefSeq | NP_199853.1 | 0 | 8 | 573 | 4 | 566 | unknown protein [Arabidopsis thaliana] |
| RefSeq | XP_002264087.1 | 0 | 2 | 573 | 1 | 559 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002303337.1 | 0 | 9 | 573 | 5 | 527 | predicted protein [Populus trichocarpa] |
