| Basic Information | |
|---|---|
| Species | Aquilegia coerulea |
| Cazyme ID | Aquca_014_00344.2 |
| Family | GT47 |
| Protein Properties | Length: 338 Molecular Weight: 38258.9 Isoelectric Point: 10.3209 |
| Chromosome | Chromosome/Scaffold: 14 Start: 1900986 End: 1904792 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GT47 | 87 | 319 | 8e-39 |
| DIKIYVYDEKEIDGLKTLMYGRDGKITADSCVKGQWGTQVKIHKLLLKSKFRTLVKEEADLFFVPSYVKCVRMMGGLNDKEINQTYVKVLTQMPYFRLSG GRNHIFIFPSGAGAHLFRSWAAYLNRSIILTPEGDRTDKRDTSAFNTWKDIIIPGNVDDSLTKSGSIQPLPLSKRKYLANFLGRAQGKSGRLQLVELAKQ FPDKLKFSGPDKLGRAEYFQHLRNAKFCLAPRG | |||
| Full Sequence |
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| Protein Sequence Length: 338 Download |
| MGSSTNRNTI NNSSNRTFTS QTPCTRTHQI GALALIITTF FFTRTFDQSF NLCNYSTNEV 60 IQSKRVTFVN NGKSVYWPDR GYGSHLDIKI YVYDEKEIDG LKTLMYGRDG KITADSCVKG 120 QWGTQVKIHK LLLKSKFRTL VKEEADLFFV PSYVKCVRMM GGLNDKEINQ TYVKVLTQMP 180 YFRLSGGRNH IFIFPSGAGA HLFRSWAAYL NRSIILTPEG DRTDKRDTSA FNTWKDIIIP 240 GNVDDSLTKS GSIQPLPLSK RKYLANFLGR AQGKSGRLQL VELAKQFPDK LKFSGPDKLG 300 RAEYFQHLRN AKFCLAPRGM CASHIVRSSR ITFPECH* |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 6.0e-26 | 88 | 320 | 245 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | NP_973879.1 | 0 | 22 | 336 | 20 | 343 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002265632.1 | 0 | 12 | 336 | 5 | 340 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002300942.1 | 0 | 11 | 336 | 5 | 341 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002307477.1 | 0 | 1 | 336 | 1 | 341 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002526175.1 | 0 | 1 | 336 | 1 | 334 | catalytic, putative [Ricinus communis] |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| DR943149 | 265 | 21 | 285 | 0 |
| DT753371 | 245 | 21 | 265 | 0 |
| DR924752 | 244 | 21 | 264 | 0 |
| BX841155 | 309 | 22 | 319 | 0 |
| GO375627 | 295 | 22 | 305 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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| Phylogeny |
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