| Basic Information | |
|---|---|
| Species | Aquilegia coerulea |
| Cazyme ID | Aquca_014_00724.2 |
| Family | CE1 |
| Protein Properties | Length: 275 Molecular Weight: 30796.8 Isoelectric Point: 6.9393 |
| Chromosome | Chromosome/Scaffold: 14 Start: 4233109 End: 4237148 |
| Description | S-formylglutathione hydrolase |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| CE1 | 25 | 271 | 0 |
| SPVLGCSMTFSVYFPPSPSPSSKFPVLYWLSGLSCTDENFIAKSGAQRAASREGVALIAPDTSPRGLNVEGEADSWDFGVGAGFYLNATQEKWKNWRMYD YVVKELPKVLSENFEQLDTSRASISGHSMGGHGALTIYLKNLDKYKSVSAFAPVSNPINCPWGQKAFSNYLGDNKSDWEEYDATCLILKHNNVLARILID QLLPNKFEEACRTAKAPVLLRMQPGYDHSYNFIATFIDDHIQHHVQA | |||
| Full Sequence |
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| Protein Sequence Length: 275 Download |
| MDLKPNEISS SKMFEGYNKR YKHYSPVLGC SMTFSVYFPP SPSPSSKFPV LYWLSGLSCT 60 DENFIAKSGA QRAASREGVA LIAPDTSPRG LNVEGEADSW DFGVGAGFYL NATQEKWKNW 120 RMYDYVVKEL PKVLSENFEQ LDTSRASISG HSMGGHGALT IYLKNLDKYK SVSAFAPVSN 180 PINCPWGQKA FSNYLGDNKS DWEEYDATCL ILKHNNVLAR ILIDQLLPNK FEEACRTAKA 240 PVLLRMQPGY DHSYNFIATF IDDHIQHHVQ ALNL* |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam00756 | Esterase | 2.0e-47 | 25 | 265 | 263 | + Putative esterase. This family contains Esterase D. However it is not clear if all members of the family have the same function. This family is related to the pfam00135 family. | ||
| COG0627 | COG0627 | 3.0e-72 | 8 | 274 | 306 | + Predicted esterase [General function prediction only] | ||
| TIGR02821 | fghA_ester_D | 2.0e-122 | 8 | 272 | 276 | + S-formylglutathione hydrolase. This model describes a protein family from bacteria, yeast, and human, with a conserved critical role in formaldehyde detoxification as S-formylglutathione hydrolase (EC 3.1.2.12). Members in eukaryotes such as the human protein are better known as esterase D (EC 3.1.1.1), an enzyme with broad specificity, although S-formylglutathione hydrolase has now been demonstrated as well [Cellular processes, Detoxification]. | ||
| PLN02442 | PLN02442 | 0 | 1 | 274 | 284 | + S-formylglutathione hydrolase | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004091 | carboxylesterase activity |
| GO:0006508 | proteolysis |
| GO:0008236 | serine-type peptidase activity |
| GO:0016023 | cytoplasmic membrane-bounded vesicle |
| GO:0018738 | S-formylglutathione hydrolase activity |
| Annotations - NR Download unfiltered results here | |||||||
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| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAM65175.1 | 0 | 13 | 274 | 1 | 272 | putative esterase D [Arabidopsis thaliana] |
| GenBank | ACJ11734.1 | 0 | 1 | 274 | 1 | 284 | S-formylglutathione hydrolase [Gossypium hirsutum] |
| RefSeq | NP_181684.1 | 0 | 6 | 274 | 6 | 284 | SFGH (S-FORMYLGLUTATHIONE HYDROLASE); S-formylglutathione hydrolase/ hydrolase, acting on ester bonds [Arabidopsis thaliana] |
| RefSeq | XP_002284489.1 | 0 | 1 | 274 | 1 | 284 | PREDICTED: hypothetical protein isoform 1 [Vitis vinifera] |
| RefSeq | XP_002308013.1 | 0 | 1 | 260 | 1 | 270 | esterase d, s-formylglutathione hydrolase [Populus trichocarpa] |
| Annotations - PDB Download unfiltered results here | |||||||
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| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3fcx_B | 0 | 7 | 273 | 5 | 281 | A Chain A, Crystal Structure Of Human Esterase D |
| PDB | 3fcx_A | 0 | 7 | 273 | 5 | 281 | A Chain A, Crystal Structure Of Human Esterase D |
| PDB | 3s8y_A | 0 | 8 | 273 | 7 | 279 | A Chain A, Bromide Soaked Structure Of An Esterase From The Oil-Degrading Bacterium Oleispira Antarctica |
| PDB | 3i6y_B | 0 | 8 | 273 | 7 | 279 | A Chain A, Structure Of An Esterase From The Oil-Degrading Bacterium Oleispira Antarctica |
| PDB | 3i6y_A | 0 | 8 | 273 | 7 | 279 | A Chain A, Structure Of An Esterase From The Oil-Degrading Bacterium Oleispira Antarctica |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| DT758794 | 285 | 1 | 275 | 0 |
| DT759710 | 285 | 1 | 275 | 0 |
| DR944783 | 275 | 2 | 266 | 0 |
| DT756717 | 268 | 1 | 258 | 0 |
| JG618514 | 281 | 4 | 274 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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| Phylogeny |
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