Basic Information | |
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Species | Aquilegia coerulea |
Cazyme ID | Aquca_020_00037.1 |
Family | GT47 |
Protein Properties | Length: 517 Molecular Weight: 58649 Isoelectric Point: 9.9008 |
Chromosome | Chromosome/Scaffold: 20 Start: 309352 End: 311627 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 184 | 467 | 0 |
EKRFRVWAYKEGEPPLVHDGPVNNIYSTEGQFIDEMDSGKNPLMAKSPDEAHVFFLPFSVANVIRYVYKPVKNFSRDRLQLLVEDYISVIANRYPYWNRS SGADHFMVACHDWAPDINDAHPELFQHFIRVLCNANASEGFQARRDVSMPEIYLPFGRLGAPNLAKPLSKRSILAFFAGGSHGHIRKILLKHWKGKDNEV QVHEYLPKGLNYTELMGQSKYCLCPSGWEVASPRVVEAIQAGCVPVIVSEDYVLPFSDVLDWSQFSVQIPVEKIPEIKNILQEI |
Full Sequence |
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Protein Sequence Length: 517 Download |
MGTLSRTTPF LLLPPLLLLF LSFSTFNKIQ LTSTSTTFSS RYSSPSYLKN IVTTTSLSSS 60 TSSISNISLT SSSATNITTT SLNISSSSTK SDHRLFNEFS NATTRTVITT TNTTYGVSNT 120 TYTPRIREKS SLNKLEDGLA RARAAIREAI QRRNYTSHKN GDFIPRGPVY RNPYAFHQSH 180 IEMEKRFRVW AYKEGEPPLV HDGPVNNIYS TEGQFIDEMD SGKNPLMAKS PDEAHVFFLP 240 FSVANVIRYV YKPVKNFSRD RLQLLVEDYI SVIANRYPYW NRSSGADHFM VACHDWAPDI 300 NDAHPELFQH FIRVLCNANA SEGFQARRDV SMPEIYLPFG RLGAPNLAKP LSKRSILAFF 360 AGGSHGHIRK ILLKHWKGKD NEVQVHEYLP KGLNYTELMG QSKYCLCPSG WEVASPRVVE 420 AIQAGCVPVI VSEDYVLPFS DVLDWSQFSV QIPVEKIPEI KNILQEIPNR KFLQLQMRVM 480 SVQKHFVVNR PAKRFDVMHM VLHSVWLRRL NLRLPS* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 4.0e-63 | 183 | 467 | 303 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ABP03873.1 | 0 | 130 | 514 | 235 | 613 | Exostosin-like [Medicago truncatula] |
EMBL | CBI21065.1 | 0 | 125 | 515 | 8 | 401 | unnamed protein product [Vitis vinifera] |
EMBL | CBI25537.1 | 0 | 89 | 515 | 46 | 476 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_002515488.1 | 0 | 65 | 514 | 34 | 468 | catalytic, putative [Ricinus communis] |
RefSeq | XP_002531945.1 | 0 | 127 | 515 | 71 | 451 | catalytic, putative [Ricinus communis] |