Basic Information | |
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Species | Aquilegia coerulea |
Cazyme ID | Aquca_021_00182.3 |
Family | GT4 |
Protein Properties | Length: 363 Molecular Weight: 40685.2 Isoelectric Point: 8.1648 |
Chromosome | Chromosome/Scaffold: 21 Start: 3806240 End: 3808747 |
Description | UDP-Glycosyltransferase superfamily protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT4 | 164 | 330 | 5.4e-40 |
YRNFLSINRFERKKNIQLAISALAILQSLNDVSEGHDLSGASLTVAGGFDKRLRENVEYLEELKSLAEKEGVSDRVKFITSCSTAERNALLSECLCVLYT PKDEHFGIVPLEAMAAEKPVIACNSGGPVETIKDGVTGFLCEPTPHDFSRAMTTFIRDHQAAEQMGK |
Full Sequence |
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Protein Sequence Length: 363 Download |
MWFLAMTKFP CTCCPGTFPV TVYGAFLPRH IFYRFHAVCA YLRCLFVALC VLLMWPSFDV 60 VLVDQVSIII PLIKTKKSTK VVFYCHFPDL LLAQHTTALR RIYRKPIDML EEATTGMADL 120 ILVNSRFTAS TFANTFKHLN ARGIQPAVLY PAVNVEQFDK STSYRNFLSI NRFERKKNIQ 180 LAISALAILQ SLNDVSEGHD LSGASLTVAG GFDKRLRENV EYLEELKSLA EKEGVSDRVK 240 FITSCSTAER NALLSECLCV LYTPKDEHFG IVPLEAMAAE KPVIACNSGG PVETIKDGVT 300 GFLCEPTPHD FSRAMTTFIR DHQAAEQMGK EARQHVSESF STKVFGQRLN QFLIDVVRKK 360 SE* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
cd03804 | GT1_wbaZ_like | 1.0e-28 | 73 | 349 | 290 | + This family is most closely related to the GT1 family of glycosyltransferases. wbaZ in Salmonella enterica has been shown to possess the mannosyl transferase activity. The members of this family are found in certain bacteria and Archaea. | ||
cd03806 | GT1_ALG11_like | 9.0e-29 | 116 | 348 | 245 | + This family is most closely related to the GT1 family of glycosyltransferases. ALG11 in yeast is involved in adding the final 1,2-linked Man to the Man5GlcNAc2-PP-Dol synthesized on the cytosolic face of the ER. The deletion analysis of ALG11 was shown to block the early steps of core biosynthesis that takes place on the cytoplasmic face of the ER and lead to a defect in the assembly of lipid-linked oligosaccharides. | ||
COG0438 | RfaG | 1.0e-31 | 27 | 360 | 342 | + Glycosyltransferase [Cell envelope biogenesis, outer membrane] | ||
cd03801 | GT1_YqgM_like | 3.0e-32 | 58 | 353 | 314 | + This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea. | ||
cd03805 | GT1_ALG2_like | 2.0e-160 | 16 | 349 | 348 | + This family is most closely related to the GT1 family of glycosyltransferases. ALG2, a 1,3-mannosyltransferase, in yeast catalyzes the mannosylation of Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. A deficiency of this enzyme causes an abnormal accumulation of Man1GlcNAc2-PP-dolichol and Man2GlcNAc2-PP-dolichol, which is associated with a type of congenital disorders of glycosylation (CDG), designated CDG-Ii, in humans. |
Gene Ontology | |
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GO Term | Description |
GO:0009058 | biosynthetic process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ACU21459.1 | 0 | 16 | 362 | 60 | 407 | unknown [Glycine max] |
EMBL | CBI20181.1 | 0 | 16 | 362 | 60 | 396 | unnamed protein product [Vitis vinifera] |
RefSeq | NP_178001.2 | 0 | 16 | 362 | 60 | 402 | glycosyl transferase family 1 protein [Arabidopsis thaliana] |
RefSeq | XP_002285480.1 | 0 | 16 | 362 | 60 | 408 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002525620.1 | 0 | 16 | 362 | 60 | 408 | alpha-1,3-mannosyltransferase, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 2f9f_A | 0.00000000000001 | 167 | 315 | 26 | 156 | A Chain A, Crystal Structure Of The Putative Mannosyl Transferase (Wbaz-1)from Archaeoglobus Fulgidus, Northeast Structural Genomics Target Gr29a |
PDB | 3c4v_B | 0.0000000000008 | 70 | 361 | 126 | 410 | A Chain A, Crystal Structure Of The Putative Mannosyl Transferase (Wbaz-1)from Archaeoglobus Fulgidus, Northeast Structural Genomics Target Gr29a |
PDB | 3c4v_A | 0.0000000000008 | 70 | 361 | 126 | 410 | A Chain A, Crystal Structure Of The Putative Mannosyl Transferase (Wbaz-1)from Archaeoglobus Fulgidus, Northeast Structural Genomics Target Gr29a |
PDB | 3c4q_B | 0.0000000000008 | 70 | 361 | 126 | 410 | A Chain A, Structure Of The Retaining Glycosyltransferase Msha : The First Step In Mycothiol Biosynthesis. Organism : Corynebacterium Glutamicum- Complex With Udp |
PDB | 3c4q_A | 0.0000000000008 | 70 | 361 | 126 | 410 | A Chain A, Structure Of The Retaining Glycosyltransferase Msha : The First Step In Mycothiol Biosynthesis. Organism : Corynebacterium Glutamicum- Complex With Udp |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
DR942573 | 271 | 93 | 363 | 0 |
DR916153 | 223 | 43 | 265 | 0 |
DR916153 | 76 | 288 | 363 | 0 |
EG522343 | 300 | 36 | 334 | 0 |
DR947098 | 212 | 152 | 363 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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