| Basic Information | |
|---|---|
| Species | Aquilegia coerulea |
| Cazyme ID | Aquca_023_00154.2 |
| Family | GT1 |
| Protein Properties | Length: 601 Molecular Weight: 66711.5 Isoelectric Point: 5.3803 |
| Chromosome | Chromosome/Scaffold: 23 Start: 3193012 End: 3201972 |
| Description | UDP-Glycosyltransferase superfamily protein |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
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| Family | Start | End | Evalue |
| GT1 | 268 | 563 | 0 |
| DTGLPFRAQAIIANPPSYGRPTHEFPHPLARVGQSAGYRLSYLIVDLIIWWGIRTFINDFRRKKLKLAPIAYFSTYNNSISHLPTGYMWSPYLVPKPTDW GALVDVVGFCFLNLGTKYLPSEQFSEWIQKGPMPIYIGFGSMPLEDAKKTTLVILEALKDTGQRGIIDRGWGDLGLCLDVPDNVFLLEDCPHDWLFPQCV AVVHHGGAGTTATGLRAGCPTTIVPFFGDQFFWGDRIQQIGLGPTPIPIYELNVENLSNAIRFMLQPEVKERANQLAKKIENEDGVAAAVDAFHRH | |||
| Full Sequence |
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| Protein Sequence Length: 601 Download |
| MEGITGVIDH IGRLNDEVEV EVGDNFKVVV VEEETLGLND STNGKHSSVK ELNDGTSILR 60 ALEHCNTAPV SVHKDTIVEG HEAILSRSKT EKKERSKHDM KLDKLSDLEK KKIIVNLVKI 120 QNDGTVEVDV AQSDPVASEL LELDAVDVTQ NDDNNSIMEL SRAIPRLKIA ILVVGTRGDV 180 QPFLAIAKRL QEFGHYVRLA THANFCTFVK SAGIDFYPLG GDARVLAGYM ARNKGLFPSA 240 PREITIQRTQ MKAIIDSMLS ACTEPDLDTG LPFRAQAIIA NPPSYGRPTH EFPHPLARVG 300 QSAGYRLSYL IVDLIIWWGI RTFINDFRRK KLKLAPIAYF STYNNSISHL PTGYMWSPYL 360 VPKPTDWGAL VDVVGFCFLN LGTKYLPSEQ FSEWIQKGPM PIYIGFGSMP LEDAKKTTLV 420 ILEALKDTGQ RGIIDRGWGD LGLCLDVPDN VFLLEDCPHD WLFPQCVAVV HHGGAGTTAT 480 GLRAGCPTTI VPFFGDQFFW GDRIQQIGLG PTPIPIYELN VENLSNAIRF MLQPEVKERA 540 NQLAKKIENE DGVAAAVDAF HRHLPQELPE PTVSIEEEDP PHPFQWLFQI IEKTCCLPCI 600 * |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| TIGR01426 | MGT | 2.0e-5 | 439 | 558 | 121 | + glycosyltransferase, MGT family. This model describes the MGT (macroside glycosyltransferase) subfamily of the UDP-glucuronosyltransferase family. Members include a number of glucosyl transferases for macrolide antibiotic inactivation, but also include transferases of glucose-related sugars for macrolide antibiotic production [Cellular processes, Toxin production and resistance]. | ||
| pfam03033 | Glyco_transf_28 | 1.0e-20 | 169 | 290 | 122 | + Glycosyltransferase family 28 N-terminal domain. The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). This N-terminal domain contains the acceptor binding site and likely membrane association site. This family also contains a large number of proteins that probably have quite distinct activities. | ||
| COG1819 | COG1819 | 1.0e-35 | 166 | 562 | 411 | + Glycosyl transferases, related to UDP-glucuronosyltransferase [Carbohydrate transport and metabolism / Signal transduction mechanisms] | ||
| cd03784 | GT1_Gtf_like | 8.0e-106 | 168 | 563 | 416 | + This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the oxidatively cross-linked heptapeptide core of vancomycin group antibiotics. The core structure is important for the bioactivity of the antibiotics. | ||
| Gene Ontology | |
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| GO Term | Description |
| GO:0005975 | carbohydrate metabolic process |
| GO:0008152 | metabolic process |
| GO:0016758 | transferase activity, transferring hexosyl groups |
| GO:0030259 | lipid glycosylation |
| Annotations - NR Download unfiltered results here | |||||||
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| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ABC96116.1 | 0 | 42 | 599 | 127 | 699 | sterol glucosyltransferase [Withania somnifera] |
| EMBL | CBI18214.1 | 0 | 3 | 599 | 72 | 696 | unnamed protein product [Vitis vinifera] |
| RefSeq | XP_002265312.1 | 0 | 3 | 599 | 56 | 680 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002302172.1 | 0 | 5 | 599 | 3 | 615 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002524293.1 | 0 | 61 | 599 | 17 | 577 | transferase, transferring glycosyl groups, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
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| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3h4t_A | 3e-31 | 167 | 556 | 1 | 374 | A Chain A, Crystal Structure Of Udp-Glucosyltransferase Gtfb |
| PDB | 3h4i_A | 3e-31 | 167 | 556 | 1 | 374 | A Chain A, Chimeric Glycosyltransferase For The Generation Of Novel Natural Products |
| PDB | 1iir_A | 1e-30 | 167 | 577 | 1 | 409 | A Chain A, Crystal Structure Of Udp-Glucosyltransferase Gtfb |
| PDB | 1pnv_B | 4e-25 | 167 | 556 | 1 | 380 | A Chain A, Crystal Structure Of Udp-Glucosyltransferase Gtfb |
| PDB | 1pnv_A | 4e-25 | 167 | 556 | 1 | 380 | A Chain A, Crystal Structure Of Udp-Glucosyltransferase Gtfb |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| HO801427 | 423 | 197 | 597 | 0 |
| DT547914 | 322 | 185 | 486 | 0 |
| GT034671 | 318 | 241 | 538 | 0 |
| CO103793 | 276 | 180 | 435 | 0 |
| HO801427 | 208 | 167 | 349 | 1e-19 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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