Basic Information | |
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Species | Aquilegia coerulea |
Cazyme ID | Aquca_030_00048.1 |
Family | GT47 |
Protein Properties | Length: 471 Molecular Weight: 54289.2 Isoelectric Point: 9.8837 |
Chromosome | Chromosome/Scaffold: 30 Start: 324727 End: 327182 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 109 | 409 | 0 |
KNLKIYIYDLPSKYNKDWLSNKRCSNHLFASEVAIHKALMESDVRTLDPLEADFFFVPVYVSCNFSTINGFPALGHARPLLSSAVQFISSQMPFWNRSNG GSDHIFVASHDYGACFHAMEDVAIADGIPEFMKKSIILQTFGVEFLHPCQNVENVLIPPYISPESIRSTLEMLPVNGKRDIWVFFRGKMEVHPKNVSGRF YSKKVRTVIWDTFNRHKKFYLKRHRFDGYQTEIARSTFCLCPLGWAPWSPRLVESIALGCVPVIIADGIRLSFSSTVRWPDISLRVAEKDVGDLANILEH V |
Full Sequence |
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Protein Sequence Length: 471 Download |
MVDRSTKNRG FYCRMKFLHK HGRHHYDNNK NNNSSFYYRY FKWILWVCLS LYFFTSYLIT 60 SSHNKTTSLP TTKISSSKTN FISRALFESN NSVLQQPILT KASISSELKN LKIYIYDLPS 120 KYNKDWLSNK RCSNHLFASE VAIHKALMES DVRTLDPLEA DFFFVPVYVS CNFSTINGFP 180 ALGHARPLLS SAVQFISSQM PFWNRSNGGS DHIFVASHDY GACFHAMEDV AIADGIPEFM 240 KKSIILQTFG VEFLHPCQNV ENVLIPPYIS PESIRSTLEM LPVNGKRDIW VFFRGKMEVH 300 PKNVSGRFYS KKVRTVIWDT FNRHKKFYLK RHRFDGYQTE IARSTFCLCP LGWAPWSPRL 360 VESIALGCVP VIIADGIRLS FSSTVRWPDI SLRVAEKDVG DLANILEHVA ATNLTTIQTN 420 LWNPVNRRAM MFNNQIQHGD ATWQVLHSLS QILHRSYRRS KINSQFNFDT * 480 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-72 | 109 | 406 | 306 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAX33322.1 | 0 | 15 | 465 | 1 | 442 | secondary cell wall-related glycosyltransferase family 47 [Populus tremula x Populus tremuloides] |
GenBank | ABI64067.1 | 0 | 15 | 465 | 1 | 442 | glycosyltransferase GT47C [Populus tremula x Populus alba] |
RefSeq | XP_002275679.1 | 0 | 1 | 449 | 1 | 436 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002314302.1 | 0 | 5 | 465 | 11 | 462 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002523710.1 | 0 | 1 | 465 | 4 | 461 | transferase, putative [Ricinus communis] |