y
Basic Information | |
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Species | Aquilegia coerulea |
Cazyme ID | Aquca_030_00256.1 |
Family | GT47 |
Protein Properties | Length: 490 Molecular Weight: 56081.1 Isoelectric Point: 7.7882 |
Chromosome | Chromosome/Scaffold: 30 Start: 1846968 End: 1848437 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 83 | 408 | 0 |
VSVYVYELPAKFNLGMLKDCRHLNVYTDMCPHVANRGLGQPITGPPQSSSSSSSWFATHQFIAEMIFHARVENHPCRTLEPEGATLFYVPFYGGLHASSK FREADLVERDRLAMELVEYLIQQPWWQRKQGRDHFLALGRTAWDFMRGEVDFGANSLLNLPEVKNMSVLTVERHPWEGHNQHGIPYPSYLHPSTSDELVM WQEKMRHVERPYLFSFVGAPRTGVQKAAIRDEILRQCSKDHSSCYLLKCGRVGASKCHNPSEVLKVMTKSQFCLQAPGDSFTRRSTFDSILAGCIPVFFS PHTAYTQYTWYLPKETTEYSVYIPIP |
Full Sequence |
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Protein Sequence Length: 490 Download |
MLLRKLRSVA LMGEGNKDQT DQHLIDFQDT NKDKPPLTAH YLKHSFHSFL FISIWCLFLF 60 LFFWSSSTTN KLEEFSQKCD GSVSVYVYEL PAKFNLGMLK DCRHLNVYTD MCPHVANRGL 120 GQPITGPPQS SSSSSSWFAT HQFIAEMIFH ARVENHPCRT LEPEGATLFY VPFYGGLHAS 180 SKFREADLVE RDRLAMELVE YLIQQPWWQR KQGRDHFLAL GRTAWDFMRG EVDFGANSLL 240 NLPEVKNMSV LTVERHPWEG HNQHGIPYPS YLHPSTSDEL VMWQEKMRHV ERPYLFSFVG 300 APRTGVQKAA IRDEILRQCS KDHSSCYLLK CGRVGASKCH NPSEVLKVMT KSQFCLQAPG 360 DSFTRRSTFD SILAGCIPVF FSPHTAYTQY TWYLPKETTE YSVYIPIPEE GKTENNVDIE 420 KELKKIPKEK VERMRNTVIG LIPRMTYMHP NSTSTSSTHL KDAVDVALEK LSNYVLNFTS 480 SSLLPLPTI* 540 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 7.0e-66 | 85 | 406 | 337 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
DDBJ | BAC42883.1 | 0 | 58 | 472 | 46 | 444 | unknown protein [Arabidopsis thaliana] |
RefSeq | NP_177014.1 | 0 | 58 | 472 | 46 | 444 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002270383.1 | 0 | 81 | 475 | 121 | 499 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002300452.1 | 0 | 79 | 471 | 1 | 391 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002336132.1 | 0 | 66 | 471 | 10 | 412 | predicted protein [Populus trichocarpa] |