Basic Information | |
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Species | Aquilegia coerulea |
Cazyme ID | Aquca_030_00332.1 |
Family | GT47 |
Protein Properties | Length: 498 Molecular Weight: 56626.8 Isoelectric Point: 8.894 |
Chromosome | Chromosome/Scaffold: 30 Start: 2437269 End: 2441581 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 109 | 421 | 0 |
NSIKVYLYELPRKFTYGVIESYLIARDSDSSKLKYPGNQHSAEWFLFSDLIQKDRDDSSEIIRVLDPEDADLFYVPFFSSLSLVVNPIRPAGVVESNSGG KVYSDEEMQESLVEWLEEQVYWKRNNGWDHVFICQDPNALYKVVDRVKNGILLLSDFGRLRGDQASLVKDVILPYSHRINPFNGDIGVEERKSLLFFMGN RFRKEGGKVRDLLFQVLENQDDVIIKHGAQSRESRRMATQGMHSSKFCLHPAGDTPSACRLFDAIVSLCVPVIISDHIELPFEDAIDYNKIAIFVDSNTA VKPGYLVKKLRKV |
Full Sequence |
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Protein Sequence Length: 498 Download |
MRTLENHLPL HTRKPLKQQN HSSSSSSPSL PINGVETLMK TSSSSSSPKM AKKSVLKQTL 60 ITILLILAFY AFFNTFLSPI NPTTTKLDSN FPSESTGSSR KTSDSNSRNS IKVYLYELPR 120 KFTYGVIESY LIARDSDSSK LKYPGNQHSA EWFLFSDLIQ KDRDDSSEII RVLDPEDADL 180 FYVPFFSSLS LVVNPIRPAG VVESNSGGKV YSDEEMQESL VEWLEEQVYW KRNNGWDHVF 240 ICQDPNALYK VVDRVKNGIL LLSDFGRLRG DQASLVKDVI LPYSHRINPF NGDIGVEERK 300 SLLFFMGNRF RKEGGKVRDL LFQVLENQDD VIIKHGAQSR ESRRMATQGM HSSKFCLHPA 360 GDTPSACRLF DAIVSLCVPV IISDHIELPF EDAIDYNKIA IFVDSNTAVK PGYLVKKLRK 420 VGAKRILEYQ RELKKVKHYF EYEDPNGTVK EIWRQVSLKL PHVKLMINRE KRLVRRDLIE 480 QDCSCLCTNN TGIISTI* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-73 | 107 | 421 | 326 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CAN68074.1 | 0 | 50 | 493 | 1 | 457 | hypothetical protein [Vitis vinifera] |
RefSeq | XP_002276440.1 | 0 | 48 | 493 | 32 | 490 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002322391.1 | 0 | 50 | 497 | 1 | 457 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002460871.1 | 0 | 82 | 496 | 74 | 498 | hypothetical protein SORBIDRAFT_02g036640 [Sorghum bicolor] |
RefSeq | XP_002523645.1 | 0 | 50 | 497 | 1 | 452 | catalytic, putative [Ricinus communis] |