| Basic Information | |
|---|---|
| Species | Aquilegia coerulea |
| Cazyme ID | Aquca_034_00218.3 |
| Family | GT1 |
| Protein Properties | Length: 663 Molecular Weight: 72169.3 Isoelectric Point: 6.178 |
| Chromosome | Chromosome/Scaffold: 34 Start: 1513710 End: 1523166 |
| Description | UDP-Glycosyltransferase superfamily protein |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
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| Family | Start | End | Evalue |
| GT1 | 224 | 628 | 0 |
| RGDVQPFVAIGKRLQDYGHRVRLATHGNFKEFVLTAGLEFYPLGGDPKVLAEYMVKNKGFLPSGPSEIPIQRKQMKDIIFSLLPACKDPDLDSGIAFKAE AIIANPPAYGHAHVAEALKVPLHVFFTMPWTPTSEFPHPLSRVKQPAGYRLSYQIVDSMIWLGIRDMINDFRKKKLKLRPVTYLSGAQGSSSDVPYGYIW SPHLVPKPKDWGPKIDVVGFCFLDLASNYVPPEPLVKWLEAGKKPIYIGFGSLPVQDPQKMTQVIVEALEITGQRGIINKGWGGLGDLAEPKDFVYLLDN CPHDWLFLQCTAVVHHGGAGTTAAGLKAACPTTIVPFFGDQPFWGERVHARGVGPAPIAVDQFSLQKLVDAINFMLDPKVKECAIDLAKAMESEDGVTGA VKAFF | |||
| Full Sequence |
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| Protein Sequence Length: 663 Download |
| MVSGKEKESS STDLVEEEKC DNNGKKESSD DESVAVNGRK SSSSSSSSCL SSDKNDEEIL 60 PSSSGGELET IEKKSGVEVV DHSLKHSSDI GSSSASGNAE RSLPRAKTLP GETSGADKVE 120 SNLKEAKMER SNTDRRRQSS IRGEQTAQIF DDNMSVREKI KMLNRIATVK DDGTVEFEIP 180 GNLKADGLDF GTDVCSEAVD EPLDPTDLQY IPPLQIVILI VGTRGDVQPF VAIGKRLQDY 240 GHRVRLATHG NFKEFVLTAG LEFYPLGGDP KVLAEYMVKN KGFLPSGPSE IPIQRKQMKD 300 IIFSLLPACK DPDLDSGIAF KAEAIIANPP AYGHAHVAEA LKVPLHVFFT MPWTPTSEFP 360 HPLSRVKQPA GYRLSYQIVD SMIWLGIRDM INDFRKKKLK LRPVTYLSGA QGSSSDVPYG 420 YIWSPHLVPK PKDWGPKIDV VGFCFLDLAS NYVPPEPLVK WLEAGKKPIY IGFGSLPVQD 480 PQKMTQVIVE ALEITGQRGI INKGWGGLGD LAEPKDFVYL LDNCPHDWLF LQCTAVVHHG 540 GAGTTAAGLK AACPTTIVPF FGDQPFWGER VHARGVGPAP IAVDQFSLQK LVDAINFMLD 600 PKVKECAIDL AKAMESEDGV TGAVKAFFKH LPRKKPSSEP PPLPSGCLEP CFGSVKRCFG 660 CS* |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| COG1819 | COG1819 | 7.0e-33 | 216 | 625 | 416 | + Glycosyl transferases, related to UDP-glucuronosyltransferase [Carbohydrate transport and metabolism / Signal transduction mechanisms] | ||
| pfam03033 | Glyco_transf_28 | 1.0e-37 | 216 | 360 | 145 | + Glycosyltransferase family 28 N-terminal domain. The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). This N-terminal domain contains the acceptor binding site and likely membrane association site. This family also contains a large number of proteins that probably have quite distinct activities. | ||
| cd03784 | GT1_Gtf_like | 1.0e-123 | 216 | 630 | 419 | + This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the oxidatively cross-linked heptapeptide core of vancomycin group antibiotics. The core structure is important for the bioactivity of the antibiotics. | ||
| Gene Ontology | |
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| GO Term | Description |
| GO:0005975 | carbohydrate metabolic process |
| GO:0008152 | metabolic process |
| GO:0016758 | transferase activity, transferring hexosyl groups |
| GO:0030259 | lipid glycosylation |
| Annotations - NR Download unfiltered results here | |||||||
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| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| DDBJ | BAC22617.1 | 0 | 62 | 662 | 21 | 602 | UDP-glucose:sterol 3-O-glucosyltransferase [Panax ginseng] |
| EMBL | CBI37267.1 | 0 | 101 | 662 | 56 | 615 | unnamed protein product [Vitis vinifera] |
| RefSeq | NP_001052094.1 | 0 | 100 | 662 | 47 | 609 | Os04g0131900 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | XP_002265023.1 | 0 | 101 | 662 | 103 | 662 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002521125.1 | 0 | 62 | 662 | 34 | 626 | transferase, transferring glycosyl groups, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
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| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3h4t_A | 3e-30 | 214 | 637 | 1 | 387 | A Chain A, Crystal Structure Of Udp-Glucosyltransferase Gtfb |
| PDB | 3h4i_A | 3e-30 | 214 | 637 | 1 | 387 | A Chain A, Chimeric Glycosyltransferase For The Generation Of Novel Natural Products |
| PDB | 1rrv_B | 7e-23 | 214 | 637 | 1 | 405 | A Chain A, X-Ray Crystal Structure Of Tdp-Vancosaminyltransferase Gtfd As A Complex With Tdp And The Natural Substrate, Desvancosaminyl Vancomycin. |
| PDB | 1rrv_A | 7e-23 | 214 | 637 | 1 | 405 | A Chain A, X-Ray Crystal Structure Of Tdp-Vancosaminyltransferase Gtfd As A Complex With Tdp And The Natural Substrate, Desvancosaminyl Vancomycin. |
| PDB | 1iir_A | 2e-20 | 458 | 637 | 230 | 404 | A Chain A, Crystal Structure Of Udp-Glucosyltransferase Gtfb |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| GT046352 | 335 | 223 | 557 | 0 |
| GO883166 | 334 | 178 | 509 | 0 |
| DY295142 | 421 | 108 | 525 | 0 |
| DT743416 | 263 | 166 | 428 | 0 |
| GT046352 | 32 | 550 | 581 | 0.0003 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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