| Basic Information | |
|---|---|
| Species | Aquilegia coerulea |
| Cazyme ID | Aquca_040_00053.1 |
| Family | GT47 |
| Protein Properties | Length: 479 Molecular Weight: 55631.4 Isoelectric Point: 8.9721 |
| Chromosome | Chromosome/Scaffold: 40 Start: 914319 End: 917621 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GT47 | 93 | 411 | 0 |
| HQRLRVFMYDLPTRFNLAMISRKFSSDETPVNNRNFPPWPSNSGLRHQHSVEYWMMGSLMYEQASDTEWREAVRVLDPDIADVFFLPFFSSTSFNTHGHN MTDPQTEIDRQLQIDILEFLRKSQYWQRSGGRDHVIPMHHPNAFRFLRDQVNTSILIVADFGRYPKSMSRLSKDVVAPYVHVVESFIDDNSPDPFVSRTT LLFFRGRTIRKDEGIVRAKLGKILEGYKDVHYEQSFASDATIKASSQGMRTSKFCLNPAGDTPSSCRLFDAIVSHCVPVIVSDKIELPYEDELDYSQFSI FFSVKEALEPGYMVSELRK | |||
| Full Sequence |
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| Protein Sequence Length: 479 Download |
| MNSNSSSNNN SQSQTGEREN RENNSKSLLL PFITTTMSGK TLLSIISIFL ILIPLYLFIG 60 TVDLKSHFFP LSQPSTTITT TSFFCPTSSS SQHQRLRVFM YDLPTRFNLA MISRKFSSDE 120 TPVNNRNFPP WPSNSGLRHQ HSVEYWMMGS LMYEQASDTE WREAVRVLDP DIADVFFLPF 180 FSSTSFNTHG HNMTDPQTEI DRQLQIDILE FLRKSQYWQR SGGRDHVIPM HHPNAFRFLR 240 DQVNTSILIV ADFGRYPKSM SRLSKDVVAP YVHVVESFID DNSPDPFVSR TTLLFFRGRT 300 IRKDEGIVRA KLGKILEGYK DVHYEQSFAS DATIKASSQG MRTSKFCLNP AGDTPSSCRL 360 FDAIVSHCVP VIVSDKIELP YEDELDYSQF SIFFSVKEAL EPGYMVSELR KIEKERWMEM 420 WKKLKNISHH YEFQYPPKRE DAVNMLWRQV MHKLPETKLS VHRNRRLKIP DWWDLKRK* 480 |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 3.0e-66 | 95 | 412 | 326 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | NP_176908.2 | 0 | 37 | 473 | 1 | 429 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002272591.1 | 0 | 63 | 477 | 27 | 430 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002311068.1 | 0 | 96 | 473 | 2 | 380 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002456855.1 | 0 | 96 | 473 | 61 | 431 | hypothetical protein SORBIDRAFT_03g044100 [Sorghum bicolor] |
| RefSeq | XP_002512333.1 | 0 | 61 | 473 | 25 | 431 | catalytic, putative [Ricinus communis] |
