| Basic Information | |
|---|---|
| Species | Aquilegia coerulea |
| Cazyme ID | Aquca_045_00152.1 |
| Family | GT4 |
| Protein Properties | Length: 428 Molecular Weight: 49382.2 Isoelectric Point: 8.9321 |
| Chromosome | Chromosome/Scaffold: 45 Start: 1184066 End: 1187880 |
| Description | UDP-Glycosyltransferase superfamily protein |
| View CDS | |
| External Links |
|---|
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
 | |||
| Family | Start | End | Evalue |
| GT4 | 216 | 376 | 3.1e-23 |
| KIPTFLSVAQFRPEKAHTLQLEAFSIALGKLEADSPRPKLQFVGSCRNKEDEDRLQKLKDKAIELRVEKDVEFYQNLMYKNLVRLLGGAIAGIHSMIDEH FGISVVEYIAAGAIPIARNSAGPRMDIVLEEDGHQTGFLASDANEYADAILQLLRMPERER | |||
| Full Sequence |
|---|
| Protein Sequence Length: 428 Download |
| MMVEVESRER VLWCAVKAIQ EINPNLDCFI YTGDHDASPE TLILRPIDRF GVKLLHPPQV 60 VHLNRRKWIE EHTYPRFTMV GQSFGSVYLS WEALRKVTPL VYFDTSGYAF TYPLARMFGC 120 KVICYTHYPT ISSDMVSRVW RRSSIIWLSR CKVIYYTFFS WMYGFVGSCT NLAMVNSSWT 180 QSHIEKMWKI PKLTKKVYPP CDTSGLQELP LGRSNKIPTF LSVAQFRPEK AHTLQLEAFS 240 IALGKLEADS PRPKLQFVGS CRNKEDEDRL QKLKDKAIEL RVEKDVEFYQ NLMYKNLVRL 300 LGGAIAGIHS MIDEHFGISV VEYIAAGAIP IARNSAGPRM DIVLEEDGHQ TGFLASDANE 360 YADAILQLLR MPERERLEMA EAARKRVSRF SEQRFYEDFK ILQSYVFLSI EKRLILKIGG 420 KVKDWRE* |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
 | ||||||||
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| COG0438 | RfaG | 4.0e-16 | 112 | 399 | 290 | + Glycosyltransferase [Cell envelope biogenesis, outer membrane] | ||
| pfam00534 | Glycos_transf_1 | 3.0e-18 | 218 | 365 | 150 | + Glycosyl transferases group 1. Mutations in this domain of human PIGA lead to disease (Paroxysmal Nocturnal haemoglobinuria). Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars. The eukaryotic glycogen synthases may be distant members of this family. | ||
| cd03805 | GT1_ALG2_like | 1.0e-18 | 113 | 365 | 270 | + This family is most closely related to the GT1 family of glycosyltransferases. ALG2, a 1,3-mannosyltransferase, in yeast catalyzes the mannosylation of Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. A deficiency of this enzyme causes an abnormal accumulation of Man1GlcNAc2-PP-dolichol and Man2GlcNAc2-PP-dolichol, which is associated with a type of congenital disorders of glycosylation (CDG), designated CDG-Ii, in humans. | ||
| cd03806 | GT1_ALG11_like | 3.0e-176 | 9 | 398 | 403 | + This family is most closely related to the GT1 family of glycosyltransferases. ALG11 in yeast is involved in adding the final 1,2-linked Man to the Man5GlcNAc2-PP-Dol synthesized on the cytosolic face of the ER. The deletion analysis of ALG11 was shown to block the early steps of core biosynthesis that takes place on the cytoplasmic face of the ER and lead to a defect in the assembly of lipid-linked oligosaccharides. | ||
| PLN02949 | PLN02949 | 0 | 9 | 400 | 402 | + transferase, transferring glycosyl groups | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0009058 | biosynthetic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ABA99697.1 | 0 | 9 | 399 | 46 | 446 | glycosyl transferase, group 1 family protein, expressed [Oryza sativa (japonica cultivar-group)] |
| RefSeq | NP_181548.2 | 0 | 9 | 407 | 50 | 458 | glycosyl transferase family 1 protein [Arabidopsis thaliana] |
| RefSeq | XP_002318120.1 | 0 | 9 | 400 | 53 | 454 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002443441.1 | 0 | 9 | 399 | 47 | 447 | hypothetical protein SORBIDRAFT_08g019540 [Sorghum bicolor] |
| RefSeq | XP_002528312.1 | 0 | 9 | 400 | 52 | 453 | glycosyl transferase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2xa1_B | 0.000005 | 312 | 389 | 324 | 396 | A Chain A, Crystal Structure Of Trehalose Synthase Tret From P. Horikoshii (Seleno Derivative) |
| PDB | 2xa1_A | 0.000005 | 312 | 389 | 324 | 396 | A Chain A, Crystal Structure Of Trehalose Synthase Tret From P. Horikoshii (Seleno Derivative) |
| PDB | 2x6r_B | 0.000005 | 312 | 389 | 324 | 396 | A Chain A, Crystal Structure Of Trehalose Synthase Tret From P. Horikoshii (Seleno Derivative) |
| PDB | 2x6r_A | 0.000005 | 312 | 389 | 324 | 396 | A Chain A, Crystal Structure Of Trehalose Synthase Tret From P. Horikoshii (Seleno Derivative) |
| PDB | 2x6q_B | 0.000005 | 312 | 389 | 324 | 396 | A Chain A, Crystal Structure Of Trehalose Synthase Tret From P. Horikoshi |
| Hydropathy |
|---|
 |
| EST Download unfiltered results here | ||||
|---|---|---|---|---|
 | ||||
| Hit | Length | Start | End | EValue |
| DY263372 | 343 | 9 | 339 | 0 |
| GO840899 | 309 | 67 | 365 | 0 |
| DY299378 | 284 | 9 | 282 | 0 |
| DY269908 | 285 | 9 | 283 | 0 |
| DY295841 | 361 | 9 | 355 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
|---|
 |
| Phylogeny |
|---|
 |