Basic Information | |
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Species | Aquilegia coerulea |
Cazyme ID | Aquca_058_00216.4 |
Family | GT41 |
Protein Properties | Length: 554 Molecular Weight: 62402.6 Isoelectric Point: 7.6725 |
Chromosome | Chromosome/Scaffold: 58 Start: 1315697 End: 1319964 |
Description | Tetratricopeptide repeat (TPR)-like superfamily protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT41 | 161 | 321 | 0 |
NEGGGGRLRVGYVSSDFGNHPLSHLMGSVFGMHNRENVEVFCYALSQNDGTEWRQRIQSEAEHFVDVSAMSSDLIARMINEDKIQILINLNGYTKGARNE IFAMQPAPIQVSYMGFPGTTGATYIDYLVTDEFVSPTRYSHIYSEKLVHLPHCYFVNDYKQ | |||
GT41 | 334 | 533 | 0 |
KRSDYGLPEDKFIFACFNQLYKMDPEIFITWCNILKRVPNSAIWLLRFPAAGEARLRAYAAAQGVKPDQIIFTDVAMKNEHIRRSSLADLFLDTPLCNAH TTGTDILWAGLPMVTLPLEKMATRVAGSLCLATGVGEEMIVSSMKEYEEKAVSLAENRPKLQALTNKLKAARLTCPLFDTARWVKNLERAYFKMWNLYCS |
Full Sequence |
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Protein Sequence Length: 554 Download |
MAADVLVNRG NTFKEIGRVS EAIQDYVRAV NVRPNMAEAH ANLASAYKDS GLVEAAIKSY 60 RQALLLRPDF PEATCNLLHT LQCVCNWDDR ESKFSEVEGI IRRQIKMSVL PSVQPFHAIA 120 YPIDPNLALD ISCKYAAHCS LIASRYALPP FNHPLPVPIK NEGGGGRLRV GYVSSDFGNH 180 PLSHLMGSVF GMHNRENVEV FCYALSQNDG TEWRQRIQSE AEHFVDVSAM SSDLIARMIN 240 EDKIQILINL NGYTKGARNE IFAMQPAPIQ VSYMGFPGTT GATYIDYLVT DEFVSPTRYS 300 HIYSEKLVHL PHCYFVNDYK QKNRDVLDLV SRHKRSDYGL PEDKFIFACF NQLYKMDPEI 360 FITWCNILKR VPNSAIWLLR FPAAGEARLR AYAAAQGVKP DQIIFTDVAM KNEHIRRSSL 420 ADLFLDTPLC NAHTTGTDIL WAGLPMVTLP LEKMATRVAG SLCLATGVGE EMIVSSMKEY 480 EEKAVSLAEN RPKLQALTNK LKAARLTCPL FDTARWVKNL ERAYFKMWNL YCSGRHPQPF 540 KVTENDAEFP CNR* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
cd00189 | TPR | 4.0e-9 | 3 | 69 | 67 | + Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]-X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans in various subcellular locations; involved in a variety of functions including protein-protein interactions, but common features in the interaction partners have not been defined; involved in chaperone, cell-cycle, transciption, and protein transport complexes; the number of TPR motifs varies among proteins (1,3-11,13 15,16,19); 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accomodate an alpha-helix of a target protein; it has been proposed that TPR proteins preferably interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes; examples of TPR-proteins include, Cdc16p, Cdc23p and Cdc27p components of the cyclosome/APC, the Pex5p/Pas10p receptor for peroxisomal targeting signals, the Tom70p co-receptor for mitochondrial targeting signals, Ser/Thr phosphatase 5C and the p110 subunit of O-GlcNAc transferase; three copies of the repeat are present here | ||
cd00189 | TPR | 6.0e-13 | 4 | 89 | 86 | + Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]-X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans in various subcellular locations; involved in a variety of functions including protein-protein interactions, but common features in the interaction partners have not been defined; involved in chaperone, cell-cycle, transciption, and protein transport complexes; the number of TPR motifs varies among proteins (1,3-11,13 15,16,19); 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accomodate an alpha-helix of a target protein; it has been proposed that TPR proteins preferably interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes; examples of TPR-proteins include, Cdc16p, Cdc23p and Cdc27p components of the cyclosome/APC, the Pex5p/Pas10p receptor for peroxisomal targeting signals, the Tom70p co-receptor for mitochondrial targeting signals, Ser/Thr phosphatase 5C and the p110 subunit of O-GlcNAc transferase; three copies of the repeat are present here | ||
pfam13844 | Glyco_transf_41 | 6.0e-72 | 335 | 528 | 194 | + Glycosyl transferase family 41. This family of glycosyltransferases includes O-linked beta-N-acetylglucosamine (O-GlcNAc) transferase, an enzyme which catalyzes the addition of O-GlcNAc to serine and threonine residues. In addition to its function as an O-GlcNAc transferase, human OGT, also appears to proteolytically cleave the epigenetic cell-cycle regulator HCF-1. | ||
pfam13844 | Glyco_transf_41 | 1.0e-73 | 168 | 328 | 167 | + Glycosyl transferase family 41. This family of glycosyltransferases includes O-linked beta-N-acetylglucosamine (O-GlcNAc) transferase, an enzyme which catalyzes the addition of O-GlcNAc to serine and threonine residues. In addition to its function as an O-GlcNAc transferase, human OGT, also appears to proteolytically cleave the epigenetic cell-cycle regulator HCF-1. | ||
COG3914 | Spy | 5.0e-101 | 3 | 531 | 538 | + Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones] |
Gene Ontology | |
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GO Term | Description |
GO:0005515 | protein binding |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | XP_002270163.1 | 0.00008 | 1 | 77 | 196 | 272 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002270163.1 | 0 | 1 | 553 | 434 | 986 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002270163.1 | 0.0000007 | 3 | 89 | 266 | 352 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002270163.1 | 0.00001 | 3 | 121 | 130 | 235 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002270163.1 | 0.0001 | 8 | 80 | 237 | 309 | PREDICTED: hypothetical protein [Vitis vinifera] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 4gz6_D | 0 | 3 | 331 | 77 | 407 | A Chain A, Crystal Structure Of Raucaffricine Glucosidase From Ajmaline Biosynthesis Pathway |
PDB | 4gz6_D | 0 | 316 | 537 | 495 | 715 | A Chain A, Crystal Structure Of Raucaffricine Glucosidase From Ajmaline Biosynthesis Pathway |
PDB | 4gz6_D | 0.000000007 | 3 | 82 | 9 | 88 | A Chain A, Crystal Structure Of Raucaffricine Glucosidase From Ajmaline Biosynthesis Pathway |
PDB | 4gz6_C | 0 | 3 | 331 | 77 | 407 | A Chain A, Crystal Structure Of Raucaffricine Glucosidase From Ajmaline Biosynthesis Pathway |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
HO795247 | 461 | 94 | 554 | 0 |
HO778725 | 450 | 105 | 554 | 0 |
GT034150 | 327 | 201 | 527 | 0 |
GO881553 | 332 | 169 | 500 | 0 |
HO795247 | 50 | 42 | 91 | 3e-17 |
Sequence Alignments (This image is cropped. Click for full image.) |
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