| Basic Information | |
|---|---|
| Species | Aquilegia coerulea |
| Cazyme ID | Aquca_062_00017.1 |
| Family | GH29 |
| Protein Properties | Length: 511 Molecular Weight: 57219.5 Isoelectric Point: 5.2846 |
| Chromosome | Chromosome/Scaffold: 62 Start: 549372 End: 552424 |
| Description | alpha-L-fucosidase 1 |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GH29 | 37 | 334 | 0 |
| SQLSWQFGNMALFLHFGTNTFTDTEWGTGHVDPSIFNPTNLDPHQWVQVAKDAGFSRVILTAKHHDGFCLWPSDYTDYSVKSSPWKNGTGDIVAELAAAA REAGLGLGLYLSPWDRHEACYGKTLEYNEYYIAQMTELLTRYGDIKEVWLDGAKGEGEKDMEYFFESWFSLIHQLQPGAVIFSDGGPDTRWVGDEAGIAA STCWSLFNSSSALIGNTDYEYSSGGDPYGHNWVPAECDVSIRPGWFWHATELPKSAITLLDLYYKSVGRNCLLLLNVPPNSSGLISDEDVQALQEFTK | |||
| Full Sequence |
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| Protein Sequence Length: 511 Download |
| MMMKKFYLMI IFLSFSFSSS ALKRPPPLPI LPLPSASQLS WQFGNMALFL HFGTNTFTDT 60 EWGTGHVDPS IFNPTNLDPH QWVQVAKDAG FSRVILTAKH HDGFCLWPSD YTDYSVKSSP 120 WKNGTGDIVA ELAAAAREAG LGLGLYLSPW DRHEACYGKT LEYNEYYIAQ MTELLTRYGD 180 IKEVWLDGAK GEGEKDMEYF FESWFSLIHQ LQPGAVIFSD GGPDTRWVGD EAGIAASTCW 240 SLFNSSSALI GNTDYEYSSG GDPYGHNWVP AECDVSIRPG WFWHATELPK SAITLLDLYY 300 KSVGRNCLLL LNVPPNSSGL ISDEDVQALQ EFTKLRQAIF SSNIAKNGVL TASSTRGGTT 360 DTRYAPSSVL EENIHSYWAP EENQNEWMIY LNLAESTLFN MLQVQEPIHM GQRIIKFHLD 420 ILTGEGDWKT VTSGTTVGYQ RLLRFLTVKS KVLRFVIDKS RADPLISYLG IYLDTFSITT 480 TESNRSSHSY FSGSEVIQLK GYNQSHRASI * |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam01120 | Alpha_L_fucos | 3.0e-28 | 72 | 334 | 280 | + Alpha-L-fucosidase. | ||
| smart00812 | Alpha_L_fucos | 1.0e-29 | 72 | 363 | 318 | + Alpha-L-fucosidase. O-Glycosyl hydrolases (EC 3.2.1.-) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site. Because the fold of proteins is better conserved than their sequences, some of the families can be grouped in 'clans'. Family 29 encompasses alpha-L-fucosidases, which is a lysosomal enzyme responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. Deficiency of alpha-L-fucosidase results in the lysosomal storage disease fucosidosis. | ||
| COG3669 | COG3669 | 1.0e-55 | 35 | 472 | 461 | + Alpha-L-fucosidase [Carbohydrate transport and metabolism] | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004560 | alpha-L-fucosidase activity |
| GO:0005975 | carbohydrate metabolic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | NP_180377.2 | 0 | 24 | 485 | 28 | 490 | ATFUC1 (alpha-L-fucosidase 1); alpha-L-fucosidase [Arabidopsis thaliana] |
| Swiss-Prot | Q8GW72 | 0 | 24 | 485 | 28 | 490 | FUCO1_ARATH RecName: Full=Alpha-L-fucosidase 1; AltName: Full=Alpha-L-fucoside fucohydrolase; AltName: Full=Alpha-1,3/4-fucosidase; Short=AtFUC1; Flags: Precursor |
| RefSeq | XP_002276131.1 | 0 | 35 | 495 | 51 | 509 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002313533.1 | 0 | 35 | 477 | 15 | 457 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002523703.1 | 0 | 35 | 498 | 64 | 529 | alpha-l-fucosidase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3ues_B | 0 | 34 | 467 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis Complexed With Deoxyfuconojirimycin |
| PDB | 3ues_A | 0 | 34 | 467 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis Complexed With Deoxyfuconojirimycin |
| PDB | 3mo4_B | 0 | 34 | 467 | 21 | 473 | A Chain A, The Crystal Structure Of An Alpha-(1-3,4)-Fucosidase From Bifidobacterium Longum Subsp. Infantis Atcc 15697 |
| PDB | 3mo4_A | 0 | 34 | 467 | 21 | 473 | A Chain A, The Crystal Structure Of An Alpha-(1-3,4)-Fucosidase From Bifidobacterium Longum Subsp. Infantis Atcc 15697 |
| PDB | 3uet_B | 0 | 34 | 467 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis D172aE217A MUTANT COMPLEXED WITH LACTO-N- Fucopentaose Ii |
