| Basic Information | |
|---|---|
| Species | Brassica rapa |
| Cazyme ID | Bra002253 |
| Family | GT47 |
| Protein Properties | Length: 587 Molecular Weight: 67865.7 Isoelectric Point: 10.0361 |
| Chromosome | Chromosome/Scaffold: 10 Start: 10649980 End: 10652358 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 255 | 537 | 0 |
| RLLKVYVYKEGSRPIFHTPILKGLYASEGWFMKLMEGNKRYTVKDPRRANLYYMPFSARMLEYTLYVRNSHNRTNLRQFLKEYTEHISSKYPFFNRTGGA DHFLVACHDWAPYETRHHMEHCIKALCNADVTAGFKIGRDISLPETYVRAAKNPLRDLGGKPPSQRRILAFYAGSMHGYLRTILLQHWKDKDPDMRIYGR MPLGVASKMNYIEQMKSSKYCLCPKGYEVNSPRVVESIFYECVPVIISDNFVPPFFEVLDWSAFSVIVAEKDIPRLKEILMSI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 587 Download |
| MEIRSELRKL SRSGKPTWAV LVAILALTHI LLLLSYGRYL LPDGRRLKLP NEHNALLTPS 60 QNGLLRNTLA VNVSAAPTGL LETNGSGLRN ETEDDEGFVD IVDFESFEDV NDSVIVKEVA 120 GSNASDNLFP SEKIVMQNVS LQSQKNSGGS AIAAPVLENS SLLVTKKVSK KKKKMRCDLP 180 PKTVTPIDEM NRILTRHRRS SRAMRPRWSS RRDEEMLAAR KEIENAPLVT IDRELYPPIF 240 RNVSMFKRSY ELMERLLKVY VYKEGSRPIF HTPILKGLYA SEGWFMKLME GNKRYTVKDP 300 RRANLYYMPF SARMLEYTLY VRNSHNRTNL RQFLKEYTEH ISSKYPFFNR TGGADHFLVA 360 CHDWAPYETR HHMEHCIKAL CNADVTAGFK IGRDISLPET YVRAAKNPLR DLGGKPPSQR 420 RILAFYAGSM HGYLRTILLQ HWKDKDPDMR IYGRMPLGVA SKMNYIEQMK SSKYCLCPKG 480 YEVNSPRVVE SIFYECVPVI ISDNFVPPFF EVLDWSAFSV IVAEKDIPRL KEILMSIPEE 540 KYVKMQMAVR KAQRHFLWHA KPERYDLFHM VLHSIWYNRV FQVKRR* 600 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 8.0e-70 | 253 | 537 | 305 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CAN76867.1 | 0 | 185 | 584 | 264 | 711 | hypothetical protein [Vitis vinifera] |
| EMBL | CAN76867.1 | 0 | 204 | 582 | 1012 | 1390 | hypothetical protein [Vitis vinifera] |
| RefSeq | NP_197468.1 | 0 | 1 | 586 | 1 | 600 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002283936.1 | 0 | 179 | 586 | 1 | 410 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002514248.1 | 0 | 117 | 586 | 205 | 676 | catalytic, putative [Ricinus communis] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
