| Basic Information | |
|---|---|
| Species | Brassica rapa |
| Cazyme ID | Bra002287 |
| Family | GT47 |
| Protein Properties | Length: 458 Molecular Weight: 52132 Isoelectric Point: 9.2804 |
| Chromosome | Chromosome/Scaffold: 10 Start: 10485080 End: 10488225 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 124 | 408 | 0 |
| EKKFKVWVYREGEIPLVHMGPMNSIYSIEGQFMDEISRAMSPFAASHPDEAHTFLIPVSIANVVHYLYRPLVTFSRKQLHNVFLDYVNVVAHKYPYWNRS QGADHFFVSCHDWAPDVSGSNPEMLKNMIRVLCNANTSEGFMPQRDVSIPEINIPGGHLGPPHLSSSSGHDRPILAFFAGGSHGYIRKILLKHWKDKDEE VQVHEYLPKNQDYFKLMSKARFCLCPSGYEVASPRIVASINLGCVPVIISDHYALPFSDVLDWSKFTIHIPSEKIPEIKTILKNV | |||
| Full Sequence |
|---|
| Protein Sequence Length: 458 Download |
| MRFSLAPTLL LLVLLLFYQH HSSSNLNSNT LSSFVDATSL ALSPSPFLSM EFSSHSSNFT 60 LIPSAQKKEK TRNGIEEGLA KSRAAIHEAV RSKKYASENE ETFVPHGAVY RNAYAFHQSH 120 IEMEKKFKVW VYREGEIPLV HMGPMNSIYS IEGQFMDEIS RAMSPFAASH PDEAHTFLIP 180 VSIANVVHYL YRPLVTFSRK QLHNVFLDYV NVVAHKYPYW NRSQGADHFF VSCHDWAPDV 240 SGSNPEMLKN MIRVLCNANT SEGFMPQRDV SIPEINIPGG HLGPPHLSSS SGHDRPILAF 300 FAGGSHGYIR KILLKHWKDK DEEVQVHEYL PKNQDYFKLM SKARFCLCPS GYEVASPRIV 360 ASINLGCVPV IISDHYALPF SDVLDWSKFT IHIPSEKIPE IKTILKNVSG RRYLVLQRRV 420 LQVQRHFVIN RPSQPFDMLR MLLHSVWLRR LNIGLHL* 480 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 9.0e-62 | 123 | 408 | 304 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI25529.1 | 0 | 75 | 455 | 7 | 386 | unnamed protein product [Vitis vinifera] |
| RefSeq | NP_197526.4 | 0 | 50 | 455 | 1 | 407 | catalytic [Arabidopsis thaliana] |
| Swiss-Prot | Q3E9A4 | 0 | 17 | 455 | 26 | 465 | GLYT5_ARATH RecName: Full=Probable glycosyltransferase At5g20260 |
| RefSeq | XP_002266490.1 | 0 | 75 | 455 | 7 | 385 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002531945.1 | 0 | 7 | 455 | 15 | 450 | catalytic, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2jhp_A | 0.007 | 295 | 384 | 367 | 457 | A Chain A, Structure Of The Thermostable Gh51 Alpha-L-Arabinofuranosidase From Thermotoga Petrophila Rku-1 |
| PDB | 2jhc_A | 0.007 | 295 | 384 | 367 | 457 | A Chain A, Structure Of The Thermostable Gh51 Alpha-L-Arabinofuranosidase From Thermotoga Petrophila Rku-1 |
| PDB | 2jha_A | 0.007 | 295 | 384 | 367 | 457 | A Chain A, Structure Of The Thermostable Gh51 Alpha-L-Arabinofuranosidase From Thermotoga Petrophila Rku-1 |
| PDB | 2jh9_A | 0.007 | 295 | 384 | 367 | 457 | A Chain A, Structure Of The Thermostable Gh51 Alpha-L-Arabinofuranosidase From Thermotoga Petrophila Rku-1 |
| PDB | 2jh8_A | 0.007 | 295 | 384 | 367 | 457 | A Chain A, The Structure Of Bluetongue Virus Vp4 Reveals A Multifunctional Rna-capping Production-line |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
