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Basic Information | |
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Species | Brassica rapa |
Cazyme ID | Bra003790 |
Family | GT47 |
Protein Properties | Length: 763 Molecular Weight: 87438.5 Isoelectric Point: 9.7257 |
Chromosome | Chromosome/Scaffold: 07 Start: 15073125 End: 15076687 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 375 | 695 | 0 |
CGVLKVFMYDLPSEFHFGLLNWHKKGSETWPSVKNVSTVPSYPGGLNRQHSVEYWLTLDLLASETPEVKRPCSAMRVKSSKEADVVFVPFFSSLSYNRKS KLSGNETSSVDRLLQERLVEFLKSRDEWKRFGGKDHLIVAHHPNSLLYARNSLGSAMFVLSDFGRYPSSIANLEKDVIAPYVHVVKTVSNNESAPFEKRP VLAYFQGAIYRKDGGTIRQELYNLLKDEKDVHFAFGTVRGNGTKQTGKGMASSKFCLNIAGDTPSSNRLFDSIVSHCVPVIISDQIELPFEDTLDYSGFS VFVHSSEAVKKGFLVSLLRGV |
Full Sequence |
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Protein Sequence Length: 763 Download |
MVVIIDLISI RSVLESWGEN PERPRRIEDL IFSTLESDYP ANLVDFVDVF PASLHGFVGA 60 ISEHLLRDVY PSLIIHGETQ SFLKAPWPGD HDITFIVHIL LSKSAMASNV QRRGCVLVES 120 MVAERNQCVL PMPLSTGMCD IYGDLVGVYN FPEMVTQGYG VIIHGNFSIQ FVIQLFGYWS 180 REKTSWLHRV SVLMNGWDKQ RMSIYRIHKW RSMESTLLQR TRLRTNWYRV DVSKHVLDTM 240 DFYCMIWKKN KMPKWHIHHI RVRRILEKEN NRSHILLASS DKKSNSCIKV SVHLQWRETS 300 NAALLHQVRK MSEKSMISSK LLFYTITVST LLFIVSSLFF LQRNDSSFTS SLVRKLILPS 360 TDLKNERTDA KPVSCGVLKV FMYDLPSEFH FGLLNWHKKG SETWPSVKNV STVPSYPGGL 420 NRQHSVEYWL TLDLLASETP EVKRPCSAMR VKSSKEADVV FVPFFSSLSY NRKSKLSGNE 480 TSSVDRLLQE RLVEFLKSRD EWKRFGGKDH LIVAHHPNSL LYARNSLGSA MFVLSDFGRY 540 PSSIANLEKD VIAPYVHVVK TVSNNESAPF EKRPVLAYFQ GAIYRKDGGT IRQELYNLLK 600 DEKDVHFAFG TVRGNGTKQT GKGMASSKFC LNIAGDTPSS NRLFDSIVSH CVPVIISDQI 660 ELPFEDTLDY SGFSVFVHSS EAVKKGFLVS LLRGVTEDQW RKKWERLKEV ARCFEYRFPS 720 QPGDSVDMIW SAVSHKLASL QFHVHRKNRY RRSEGFERSL ST* 780 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 5.0e-56 | 374 | 695 | 331 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAD55303.1 | 0 | 311 | 762 | 1 | 458 | AC008263_34 F25A4.34 [Arabidopsis thaliana] |
RefSeq | NP_565089.1 | 0 | 310 | 762 | 3 | 461 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002284930.1 | 0 | 311 | 754 | 1 | 449 | PREDICTED: hypothetical protein isoform 1 [Vitis vinifera] |
RefSeq | XP_002284932.1 | 0 | 378 | 754 | 34 | 410 | PREDICTED: hypothetical protein isoform 2 [Vitis vinifera] |
RefSeq | XP_002320639.1 | 0 | 378 | 752 | 3 | 374 | predicted protein [Populus trichocarpa] |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
DK516189 | 244 | 520 | 763 | 0 |
EX906845 | 242 | 522 | 763 | 0 |
DK539574 | 231 | 533 | 763 | 0 |
DK539574 | 26 | 508 | 533 | 0.000002 |
DK516189 | 15 | 505 | 519 | 3.1 |
Sequence Alignments (This image is cropped. Click for full image.) |
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