| Basic Information | |
|---|---|
| Species | Brassica rapa |
| Cazyme ID | Bra004088 |
| Family | GT47 |
| Protein Properties | Length: 434 Molecular Weight: 49770 Isoelectric Point: 6.6792 |
| Chromosome | Chromosome/Scaffold: 07 Start: 16769882 End: 16771650 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 51 | 366 | 0 |
| PLRVFMYDLPRKFNLAMMHPNISDVEPITAENLPSWHQTSGVGRQHSVEYWLMASLLNNGGDEEEKEAVRVLDPELADAFYVPFFSSLSFNTHGKNMTDP DTELDRLLQVELIEYLENSKYWQRSGGRDHVIPMTHPNAFRFLRQQVNASILILVDFGRYPKEIANLDKDVVSPYVHVVESFTEDVVVDDGALDPFEARS TLLYFRGNTVRKADGKIRIRLEKLLAGNSDVHYVKSIPTTQNIKVSTEGMRSSKFCLHPAGDTPSSCRLFDAIVSHCIPVIISDKIELPFEDEIDYSEFS VFFSANEALEPGFILS | |||
| Full Sequence |
|---|
| Protein Sequence Length: 434 Download |
| MYGKTISIIV LFAFLIASYS IYMGTIDPTP CFSQLGKPSP PCNTTSTKGQ PLRVFMYDLP 60 RKFNLAMMHP NISDVEPITA ENLPSWHQTS GVGRQHSVEY WLMASLLNNG GDEEEKEAVR 120 VLDPELADAF YVPFFSSLSF NTHGKNMTDP DTELDRLLQV ELIEYLENSK YWQRSGGRDH 180 VIPMTHPNAF RFLRQQVNAS ILILVDFGRY PKEIANLDKD VVSPYVHVVE SFTEDVVVDD 240 GALDPFEARS TLLYFRGNTV RKADGKIRIR LEKLLAGNSD VHYVKSIPTT QNIKVSTEGM 300 RSSKFCLHPA GDTPSSCRLF DAIVSHCIPV IISDKIELPF EDEIDYSEFS VFFSANEALE 360 PGFILSNLRQ FPKEKWLKMW ERLKNVSHHF EFQYPPKRED AVNMLWRQVK HKIPDVKLAV 420 HRHRRLKVPD WWL* 480 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 5.0e-78 | 51 | 371 | 328 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAC18793.1 | 0 | 1 | 413 | 1 | 440 | End is cut off [Arabidopsis thaliana] |
| RefSeq | NP_176908.2 | 0 | 1 | 433 | 1 | 430 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002272591.1 | 0 | 41 | 432 | 45 | 426 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002311068.1 | 0 | 51 | 432 | 1 | 380 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002512333.1 | 0 | 30 | 432 | 34 | 431 | catalytic, putative [Ricinus communis] |
