Basic Information | |
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Species | Brassica rapa |
Cazyme ID | Bra004310 |
Family | GT47 |
Protein Properties | Length: 467 Molecular Weight: 53388 Isoelectric Point: 7.3015 |
Chromosome | Chromosome/Scaffold: 07 Start: 17892746 End: 17894496 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 73 | 412 | 0 |
EQNFTVYVYDLPKEFNTNLLQNCRHLNIYTDMCPHVANNGLGQPLHPGGGDSETWFATHQFIAEMIFHARVKNHPCRTWEPNNADIFYVPFYGGLYASSV FREQNLTKRDELAVGLVDYMSGQRWWGRSNGRDHFLAFGRTAWDFMRSSDEASTDFGANILMQVPLVRNMSVLTVERQPWDGDNQFGIPYPSYFHPYTSA EMLTWQDKMRRVERPHLFSFVGGPRKGLEKAAIRDELIRQCADSSRCELLKCESGGSRCHDPMTVLGVMARSRFCLQAPGDSFTRRSTFDAMLAGCIPVF FSPHTMYTQYMWYLPDDKRSYSVFMDEKNSTLIEQELSRI |
Full Sequence |
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Protein Sequence Length: 467 Download |
MAYNKKHVKI DLWPEKEEKE KKYSKNREAL KLTVPTFLLF CSICLIFLIL LSPFTSPPQT 60 TSFAASSPPR TCEQNFTVYV YDLPKEFNTN LLQNCRHLNI YTDMCPHVAN NGLGQPLHPG 120 GGDSETWFAT HQFIAEMIFH ARVKNHPCRT WEPNNADIFY VPFYGGLYAS SVFREQNLTK 180 RDELAVGLVD YMSGQRWWGR SNGRDHFLAF GRTAWDFMRS SDEASTDFGA NILMQVPLVR 240 NMSVLTVERQ PWDGDNQFGI PYPSYFHPYT SAEMLTWQDK MRRVERPHLF SFVGGPRKGL 300 EKAAIRDELI RQCADSSRCE LLKCESGGSR CHDPMTVLGV MARSRFCLQA PGDSFTRRST 360 FDAMLAGCIP VFFSPHTMYT QYMWYLPDDK RSYSVFMDEK NSTLIEQELS RISESDVVQM 420 REAVIAMIPK MTYAHPNATN YNLPDAVDVA LEALAMQAKA KVVYSL* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 7.0e-74 | 76 | 412 | 351 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
DDBJ | BAC42883.1 | 0 | 1 | 466 | 1 | 455 | unknown protein [Arabidopsis thaliana] |
RefSeq | NP_177014.1 | 0 | 1 | 466 | 1 | 455 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002270383.1 | 0 | 78 | 462 | 125 | 503 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002300452.1 | 0 | 72 | 454 | 1 | 391 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002336132.1 | 0 | 59 | 454 | 11 | 412 | predicted protein [Populus trichocarpa] |