| Basic Information | |
|---|---|
| Species | Brassica rapa |
| Cazyme ID | Bra004854 |
| Family | GT57 |
| Protein Properties | Length: 505 Molecular Weight: 57620.1 Isoelectric Point: 8.4271 |
| Chromosome | Chromosome/Scaffold: 05 Start: 2142969 End: 2145037 |
| Description | ALG6, ALG8 glycosyltransferase family |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT57 | 16 | 498 | 0 |
| ATAVKLLLIPSYRSTDFEVHRNWLAITHSLPLSEWYFDETSQWTLDYPPFFAYFERFLSFFARLLDPKIVDLHKGLDYSADSVVYFQRITVIFSDLSLLL GVYRLTRKVETLKRNLICVLVVWSPGLLMVDHVHFQYNGFLLGWLLLSVSFLQDGRDLIGGFLFAVVLCFKHLFAVAAPVYFVYLLRHYCWAGLATGLRR LVALGSVVVAVFAAAFGPFIYNGQIQQVISRMFPFGRGLCHAYWAPNFWVFYIILDKGLAFTLRKLGFDVQVPSASFTGGLVGDSSPFAVLPQITPLTTF VMVLLAITPCLIKAWKKPQPGLVGRWIAYAYTCGFLFGWHVHEKASLHFTIPLAIVAVQSLEDAKHYFLVSIVYCYSLFPLLYEPQEYPIKVLLLLLHSM VMWLGFTALYSDEKALKEKEGGESKSKFEIGCIEKGYLIGLVLVEIVSQFLHPYFLGDRYAFMPLMLISTYCAVGIMYSWIWQ | |||
| Full Sequence |
|---|
| Protein Sequence Length: 505 Download |
| MDGDRRHLLL WFFAAATAVK LLLIPSYRST DFEVHRNWLA ITHSLPLSEW YFDETSQWTL 60 DYPPFFAYFE RFLSFFARLL DPKIVDLHKG LDYSADSVVY FQRITVIFSD LSLLLGVYRL 120 TRKVETLKRN LICVLVVWSP GLLMVDHVHF QYNGFLLGWL LLSVSFLQDG RDLIGGFLFA 180 VVLCFKHLFA VAAPVYFVYL LRHYCWAGLA TGLRRLVALG SVVVAVFAAA FGPFIYNGQI 240 QQVISRMFPF GRGLCHAYWA PNFWVFYIIL DKGLAFTLRK LGFDVQVPSA SFTGGLVGDS 300 SPFAVLPQIT PLTTFVMVLL AITPCLIKAW KKPQPGLVGR WIAYAYTCGF LFGWHVHEKA 360 SLHFTIPLAI VAVQSLEDAK HYFLVSIVYC YSLFPLLYEP QEYPIKVLLL LLHSMVMWLG 420 FTALYSDEKA LKEKEGGESK SKFEIGCIEK GYLIGLVLVE IVSQFLHPYF LGDRYAFMPL 480 MLISTYCAVG IMYSWIWQLL KILT* 540 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03155 | Alg6_Alg8 | 9.0e-92 | 15 | 497 | 498 | + ALG6, ALG8 glycosyltransferase family. N-linked (asparagine-linked) glycosylation of proteins is mediated by a highly conserved pathway in eukaryotes, in which a lipid (dolichol phosphate)-linked oligosaccharide is assembled at the endoplasmic reticulum membrane prior to the transfer of the oligosaccharide moiety to the target asparagine residues. This oligosaccharide is composed of Glc(3)Man(9)GlcNAc(2). The addition of the three glucose residues is the final series of steps in the synthesis of the oligosaccharide precursor. Alg6 transfers the first glucose residue, and Alg8 transfers the second one. In the human alg6 gene, a C->T transition, which causes Ala333 to be replaced with Val, has been identified as the cause of a congenital disorder of glycosylation, designated as type Ic OMIM:603147. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0005789 | endoplasmic reticulum membrane |
| GO:0016758 | transferase activity, transferring hexosyl groups |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAC27468.1 | 0 | 2 | 402 | 6 | 370 | putative glucosyltransferase [Arabidopsis thaliana] |
| RefSeq | NP_181994.5 | 0 | 2 | 504 | 6 | 506 | transferase, transferring glycosyl groups / transferase, transferring hexosyl groups [Arabidopsis thaliana] |
| Swiss-Prot | O80505 | 0 | 2 | 402 | 6 | 405 | ALG8_ARATH RecName: Full=Probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase; AltName: Full=Dolichyl-P-Glc:Glc1Man9GlcNAc2-PP-dolichyl glucosyltransferase; AltName: Full=Asparagine-linked glycosylation protein 8 homolog |
| RefSeq | XP_002269114.1 | 0 | 3 | 503 | 13 | 529 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002521523.1 | 0 | 9 | 503 | 18 | 490 | dolichyl glycosyltransferase, putative [Ricinus communis] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| dolichyl-diphosphooligosaccharide biosynthesis | RXN-5471 | EC-2.4.1.265 | Dol-P-Glc:Glc1Man9GlcNAc2-PP-Dol α-1,3-glucosyltransferase |
