| Basic Information | |
|---|---|
| Species | Brassica rapa |
| Cazyme ID | Bra005369 |
| Family | GT47 |
| Protein Properties | Length: 451 Molecular Weight: 50952.7 Isoelectric Point: 10.0303 |
| Chromosome | Chromosome/Scaffold: 05 Start: 5059501 End: 5061111 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 58 | 374 | 0 |
| PRVKVYMYDLPTRFTHGVIQQHAIVRGGGGMMKKPTNDVTALKYPGHQHMHEWYLFSDLNRPESDRSGSPITRVLDPADADLFYVPVFSSLSLIVNAGRP VEPGSGYSDEKMQEGLIDWLERQVWWRRNGGRDHVIPAGDPNALYRILDRVKNAVLLVSDFGRLRPDQGSFVKDVVIPYSHRVNMFTGEIGVESRNTLLF FMGNRYRKDGGKVRDLLFQVLEKEGDVTIKHGTQSRENRRAATKGMHTSKFCLNPAGDTPSACRLFDSIVSLCVPVIVSDSIELPFEDVIDYRKFSIFVE ANVALKPGFLVKMLRKI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 451 Download |
| MARKSSVLQR AAIAVVSVIA IYAILNASVS RSLPSSSDLP RQLIREERER EAPSPIQPRV 60 KVYMYDLPTR FTHGVIQQHA IVRGGGGMMK KPTNDVTALK YPGHQHMHEW YLFSDLNRPE 120 SDRSGSPITR VLDPADADLF YVPVFSSLSL IVNAGRPVEP GSGYSDEKMQ EGLIDWLERQ 180 VWWRRNGGRD HVIPAGDPNA LYRILDRVKN AVLLVSDFGR LRPDQGSFVK DVVIPYSHRV 240 NMFTGEIGVE SRNTLLFFMG NRYRKDGGKV RDLLFQVLEK EGDVTIKHGT QSRENRRAAT 300 KGMHTSKFCL NPAGDTPSAC RLFDSIVSLC VPVIVSDSIE LPFEDVIDYR KFSIFVEANV 360 ALKPGFLVKM LRKIGRKKIL EYQREMKTVR RYFDYGNPNG AVKEIWRQVS QKLPLIKLMS 420 NRDKRLVLRN STEPDCSCLC TNQTGVITSI * 480 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 4.0e-79 | 56 | 374 | 330 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAC61825.1 | 0 | 1 | 388 | 1 | 385 | unknown protein [Arabidopsis thaliana] |
| RefSeq | NP_199306.1 | 0 | 5 | 450 | 10 | 443 | ARAD2 (ARABINAN DEFICIENT 2); catalytic [Arabidopsis thaliana] |
| RefSeq | NP_850241.1 | 0 | 1 | 450 | 1 | 447 | ARAD1 (ARABINAN DEFICIENT 1); catalytic/ transferase, transferring glycosyl groups [Arabidopsis thaliana] |
| RefSeq | XP_002322391.1 | 0 | 1 | 450 | 1 | 457 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002523645.1 | 0 | 1 | 450 | 1 | 452 | catalytic, putative [Ricinus communis] |
