| Basic Information | |
|---|---|
| Species | Brassica rapa |
| Cazyme ID | Bra005559 |
| Family | GT47 |
| Protein Properties | Length: 504 Molecular Weight: 58206.9 Isoelectric Point: 8.7765 |
| Chromosome | Chromosome/Scaffold: 05 Start: 6219313 End: 6220824 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 83 | 429 | 0 |
| CAGRYIYMHDLPSIYNDDIIKDCRPLIKWFDMCPFMVNSGLGPQVLEHANKTSQVLTTKTGSWYSTNQFLLSVIFRERMKHYECLTNDSSLASAIYIPYY PGFDVSRHLWGYNTTVRDALATKLSRWLRERPEWNKMYGRDHFFVAGRIGWDFRRCSEDSEWGSNLMCLPEFSNTTMLSIETTAWTNEFAVPYPTYFHPK SVTEVRIWQRKVKSVKRRHLFCFVGAPRPTLDGSIRGEIINQCLASHGKCKFLNCNEPGNDCDNPVKIMDVFQRSVFCLQPSGDSYTRRSIFDSILAGCI PVFFHPGSGYKQYMWYFPKDYTKYSVYIPDNGMKNGTVSLRDLLGGI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 504 Download |
| MMKPVPRLRL FISVTFVLCL FVVFQIHKSD LFGKNLQITH QVNNFFISIA SSSHHQTQNL 60 TKYSNESDGD RAKQPESEET DTCAGRYIYM HDLPSIYNDD IIKDCRPLIK WFDMCPFMVN 120 SGLGPQVLEH ANKTSQVLTT KTGSWYSTNQ FLLSVIFRER MKHYECLTND SSLASAIYIP 180 YYPGFDVSRH LWGYNTTVRD ALATKLSRWL RERPEWNKMY GRDHFFVAGR IGWDFRRCSE 240 DSEWGSNLMC LPEFSNTTML SIETTAWTNE FAVPYPTYFH PKSVTEVRIW QRKVKSVKRR 300 HLFCFVGAPR PTLDGSIRGE IINQCLASHG KCKFLNCNEP GNDCDNPVKI MDVFQRSVFC 360 LQPSGDSYTR RSIFDSILAG CIPVFFHPGS GYKQYMWYFP KDYTKYSVYI PDNGMKNGTV 420 SLRDLLGGID KESILRMRNE VVKIIPKIIY TKPGLVGPKK IEDAFDIAVD RVIQRVAMVK 480 RMMEEGKDLQ GEYSQTRDLK KLE* 540 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 7.0e-57 | 83 | 413 | 346 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | NP_180833.1 | 0 | 80 | 480 | 63 | 464 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | NP_180834.1 | 0 | 1 | 503 | 1 | 502 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002321098.1 | 0 | 42 | 500 | 14 | 462 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002518606.1 | 0 | 40 | 488 | 38 | 472 | Xyloglucan galactosyltransferase KATAMARI1, putative [Ricinus communis] |
| RefSeq | XP_002518609.1 | 0 | 10 | 488 | 15 | 475 | Xyloglucan galactosyltransferase KATAMARI1, putative [Ricinus communis] |
