| Basic Information | |
|---|---|
| Species | Brassica rapa |
| Cazyme ID | Bra005780 |
| Family | GT47 |
| Protein Properties | Length: 519 Molecular Weight: 58513.7 Isoelectric Point: 9.6868 |
| Chromosome | Chromosome/Scaffold: 03 Start: 586092 End: 589101 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 187 | 468 | 0 |
| EKQFKIFVYKEGDPPLFHDGPCKSIYSMEGNFIYEMERDTHFRTNNPDKAHAFYLPLSVVKMVRYVYQRDSHDFGPIRRTVRDYIDLVSDRYPYWNRSIG ADHFILSCHDWGPEASFSHPHLGQNSIRALCNANTSERFKPRKDVSIPEINLRTGSLKGLVGGPSPSIRPILAFFAGGVHGPVRPVLLQHWENKDNDIRV HKYLPKGTSYPDMMRSSKFCLCPSGYEVAGPRIVEALYSGCVPVLINSGYVPPFSDVLNWRSFSVIVSVEDIPKLKTILTSI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 519 Download |
| MGDEDVDGKC RIMSACSSAK LFLFMVPLVL VSGFVFVNIG PKCPTSFLTS LSTTHISPPL 60 LLSSPSLPPA PAPAPAPSLQ AAKEVSLPTS ALSTKVESVQ GDKNRTIQLN PINITLVSNN 120 VTSTASSELM KKRVTKKIDK IEFELQKARV AIKAASMDDP VDDPDYVPIG PMYWNAKVFH 180 RSYLEMEKQF KIFVYKEGDP PLFHDGPCKS IYSMEGNFIY EMERDTHFRT NNPDKAHAFY 240 LPLSVVKMVR YVYQRDSHDF GPIRRTVRDY IDLVSDRYPY WNRSIGADHF ILSCHDWGPE 300 ASFSHPHLGQ NSIRALCNAN TSERFKPRKD VSIPEINLRT GSLKGLVGGP SPSIRPILAF 360 FAGGVHGPVR PVLLQHWENK DNDIRVHKYL PKGTSYPDMM RSSKFCLCPS GYEVAGPRIV 420 EALYSGCVPV LINSGYVPPF SDVLNWRSFS VIVSVEDIPK LKTILTSISP RQYLKMYRRV 480 LKVRRHFEVN SPAKRFDVFH MILHSIWVRR LNVRIREV* 540 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 8.0e-68 | 186 | 468 | 302 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| DDBJ | BAB08605.1 | 0 | 112 | 518 | 2 | 408 | unnamed protein product [Arabidopsis thaliana] |
| RefSeq | NP_001031828.1 | 0 | 1 | 518 | 1 | 518 | unknown protein [Arabidopsis thaliana] |
| RefSeq | XP_002284018.1 | 0 | 186 | 517 | 1 | 332 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002326234.1 | 0 | 186 | 513 | 1 | 328 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002528630.1 | 0 | 159 | 517 | 209 | 567 | catalytic, putative [Ricinus communis] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
