| Basic Information | |
|---|---|
| Species | Brassica rapa |
| Cazyme ID | Bra006378 |
| Family | GT47 |
| Protein Properties | Length: 499 Molecular Weight: 56352.7 Isoelectric Point: 9.5576 |
| Chromosome | Chromosome/Scaffold: 03 Start: 3262005 End: 3264587 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 104 | 414 | 0 |
| RVKVYIYEMPKKFTFDLLWLFHNTYKETSNATSNGSPVHRLIEQHSIDYWLWADLISPESQRRLKSVVRVHQQQDADFFYVPFFTTISFFLLEKQQCKAL YREALKWVTDQPAWKRSEGRDHIFPIHHPWSFKTVRKFVKNAIWLLPDMDSTGNWYKPGQVSLEKDLVLPYVPNVDICDAKCLSESAPVRTTLLFFRGRL KRNAGGKIRAKLGAELSGVKDVIITEGTAGEGGKLAAQDGMRRSLFCLCPAGDTPSSARLFDAIVSGCIPVIVSDELELPFEGLLDYNKVAVIVSSSDAI QPGWLVNHLRS | |||
| Full Sequence |
|---|
| Protein Sequence Length: 499 Download |
| MVGKQQNHSS PRFRSKSPIL TLSLFSLSLL VIVYTFSPSV SYPNPSHKTE TSFVASLEQL 60 LIHKAPMLTS QVRDDTVRGE SDDDDLRKLD SMVSESPGYP TGFRVKVYIY EMPKKFTFDL 120 LWLFHNTYKE TSNATSNGSP VHRLIEQHSI DYWLWADLIS PESQRRLKSV VRVHQQQDAD 180 FFYVPFFTTI SFFLLEKQQC KALYREALKW VTDQPAWKRS EGRDHIFPIH HPWSFKTVRK 240 FVKNAIWLLP DMDSTGNWYK PGQVSLEKDL VLPYVPNVDI CDAKCLSESA PVRTTLLFFR 300 GRLKRNAGGK IRAKLGAELS GVKDVIITEG TAGEGGKLAA QDGMRRSLFC LCPAGDTPSS 360 ARLFDAIVSG CIPVIVSDEL ELPFEGLLDY NKVAVIVSSS DAIQPGWLVN HLRSLKPSRV 420 KEFQNSLAQY SRHFVYSSPA QPLGPEDLTW RMIAGKLVNI KLHTRRSQRV VKGSRSICRC 480 DCWRPNSTAS NPLSPLLP* 540 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 2.0e-66 | 104 | 414 | 319 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI20132.1 | 0 | 112 | 489 | 1 | 378 | unnamed protein product [Vitis vinifera] |
| RefSeq | NP_197191.1 | 0 | 1 | 484 | 1 | 497 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002285599.1 | 0 | 50 | 489 | 63 | 512 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002325382.1 | 0 | 43 | 489 | 51 | 502 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002520033.1 | 0 | 43 | 489 | 50 | 503 | catalytic, putative [Ricinus communis] |
