| Basic Information | |
|---|---|
| Species | Brassica rapa |
| Cazyme ID | Bra007906 |
| Family | GT20 |
| Protein Properties | Length: 1460 Molecular Weight: 165828 Isoelectric Point: 7.2424 |
| Chromosome | Chromosome/Scaffold: 02 Start: 11753869 End: 11760645 |
| Description | trehalose-6-phosphatase synthase S8 |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT20 | 17 | 500 | 0 |
| PRERKIIVANTLPLQSKRDSETGKWSFSWDEDSLQLQLKDGFPPDTEFLYVGSLNAHVEPNEQEAVSQTLLTSFNSVATFLPKDLQEMYYRGFCKHQLWP LFHYMLPMFPDHGDRFDRKLWQAYVSANKIFSDRVMEVINPEDDYVWIQDYHLMVLPTFLRKRFNRIKLGFFLHSPFPSSEIYRTLPVRDEILRGLLNCD LIGFHTFDYARHFLSCCSRMLGLDYQSKRGHIGLDYFGRTVFIKILPVGVHMGRLESVLNLPSAAAKIKEIQEEFKGKKLVLGIDDMDIFKGISLKLLAM ESLFETYWHLRGKVVLVQIVNPARTSGKDVEEAKRETYVTAKRINERYGSLDYKPIVLIDRLVPRYEKSAYYAAADCCLVNAVRDGMNLVPYKYIVCRQG GSLVNDSSPRTSTLVVSEFIGCSPSLSGAIRVNPWDVDDVAQAVNSALKMSEAEKQLRHEKHYHYISTHDVGYWAKSFMQDLER | |||
| Full Sequence |
|---|
| Protein Sequence Length: 1460 Download |
| MTVPGIISGS SEVTSSPRER KIIVANTLPL QSKRDSETGK WSFSWDEDSL QLQLKDGFPP 60 DTEFLYVGSL NAHVEPNEQE AVSQTLLTSF NSVATFLPKD LQEMYYRGFC KHQLWPLFHY 120 MLPMFPDHGD RFDRKLWQAY VSANKIFSDR VMEVINPEDD YVWIQDYHLM VLPTFLRKRF 180 NRIKLGFFLH SPFPSSEIYR TLPVRDEILR GLLNCDLIGF HTFDYARHFL SCCSRMLGLD 240 YQSKRGHIGL DYFGRTVFIK ILPVGVHMGR LESVLNLPSA AAKIKEIQEE FKGKKLVLGI 300 DDMDIFKGIS LKLLAMESLF ETYWHLRGKV VLVQIVNPAR TSGKDVEEAK RETYVTAKRI 360 NERYGSLDYK PIVLIDRLVP RYEKSAYYAA ADCCLVNAVR DGMNLVPYKY IVCRQGGSLV 420 NDSSPRTSTL VVSEFIGCSP SLSGAIRVNP WDVDDVAQAV NSALKMSEAE KQLRHEKHYH 480 YISTHDVGYW AKSFMQDLER ACKDHYSKRC WGIGFGLGFR VLSLSPSFRK LSVEHIVPVY 540 RKAQRRAIFL DYDGTLVPES SITQDPSAEV LSVLKALCED DKNTVFIVSG RGPESLSEWL 600 SPCENLGIAA EHGYFIRWNS KKEWETCYAS TGTEWKAMVE RVMRSYMEAT DGSSIEFKES 660 ALVWHHQDAD PDFGSCQAKE LLDHLESVLA NEPVVVKKGQ HIVEVKPQGV SKGLAAEKVI 720 REMVERGEPP EMVICIGDDR SDEDMFEGML STVTNPELLI QPEVFACTVG RKPSKAKYFL 780 DDVADVLKLL KVGSPPLGFY PIFMWIRHIS YGCFHIHVDS PHLLWVLPYS CGFATSPMGA 840 SIFMWIRHIS YGCFHIHVDS PHLLWVLPYS CGFATSPMGA SIFMWIRHIS YGCFHIHVDS 900 PHLLWVLPYS CGFATSPMGA SIFMWIRHIS YGCFHIHVDS PHLLWVLPYS CGFATSPMGA 960 SIFMWIRHIS YGCFHIHVDS PHLLWVLPYS CGFATSPMGA SIFMWIRHIS YGCFHIHVDS 1020 PHLLWVLPYS CGFATSPMGA SIFMWIRHIS YGCFHIHVDS PHLLWVLPYS CGFATSPMGA 1080 SIFMWIRHIS YGCFHIHVDS PHLLWVLPYS CGFATSPMGA SIFMWIRHIS YGCFHIHVDS 1140 PHLLWVLPYS CGFATSPMGA SIFMWIRHIS YGCFHIHVDS PHLLWVLPYS CGFATSPMGA 1200 SIFMWIRHIS YGCFHIHVDS PHLLWVLPYS CGFATSPMGA SIFMWIRHIS YGCFHIHVDS 1260 PHLLWVLPYS CGFATSPMGA SIFMWIRHIS YGCFHIHVDS PHLLWVLPYS CGFATSPMGA 1320 SIFISGTSKQ ERRDLVTTTT PHIHHHHHTR TITPSPLGRP PPPPPAARLA LGGLTARREE 1380 ENQRKEKGEG EGERGGLEIF WAGSFRSLSN TPGDYAFMSK DAEKMQQLRR SRAFYSGWDS 1440 EFPNQQQEQN SEIVFGAVQ* 1500 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| PLN03063 | PLN03063 | 1.0e-153 | 18 | 779 | 797 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
| PLN02205 | PLN02205 | 0 | 1 | 779 | 800 | + alpha,alpha-trehalose-phosphate synthase [UDP-forming] | ||
| pfam00982 | Glyco_transf_20 | 0 | 19 | 500 | 486 | + Glycosyltransferase family 20. Members of this family belong to glycosyl transferase family 20. OtsA (Trehalose-6-phosphate synthase) is homologous to regions in the subunits of yeast trehalose-6-phosphate synthase/phosphate complex. | ||
| PRK14501 | PRK14501 | 0 | 20 | 779 | 766 | + putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional | ||
| cd03788 | GT1_TPS | 0 | 22 | 499 | 478 | + Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a nonreducing disaccharide present in a wide variety of organisms and may serve as a source of energy and carbon. It is characterized most notably in insect, plant, and microbial cells. Its production is often associated with a variety of stress conditions, including desiccation, dehydration, heat, cold, and oxidation. This family represents the catalytic domain of the TPS. Some members of this domain family coexist with a C-terminal trehalose phosphatase domain. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0005992 | trehalose biosynthetic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAC18810.1 | 0 | 1 | 791 | 1 | 802 | Strong similarity to trehalose-6-phosphate synthase homolog from A. thaliana chromosome 4 contig gb |
| GenBank | AAV65495.1 | 0 | 1 | 791 | 31 | 837 | trehalose 6-phosphate synthase [Gossypium hirsutum] |
| RefSeq | NP_173799.1 | 0 | 1 | 790 | 31 | 836 | ATTPS9; transferase, transferring glycosyl groups / trehalose-phosphatase [Arabidopsis thaliana] |
| RefSeq | NP_177186.2 | 0 | 1 | 791 | 31 | 832 | ATTPS8; alpha,alpha-trehalose-phosphate synthase (UDP-forming)/ transferase, transferring glycosyl groups / trehalose-phosphatase [Arabidopsis thaliana] |
| RefSeq | XP_002521023.1 | 0 | 1 | 791 | 31 | 837 | trehalose-6-phosphate synthase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1gz5_D | 0 | 99 | 500 | 70 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 1gz5_C | 0 | 99 | 500 | 70 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 1gz5_B | 0 | 99 | 500 | 70 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 1gz5_A | 0 | 99 | 500 | 70 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 2wtx_D | 0 | 99 | 500 | 71 | 453 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| trehalose biosynthesis I | TREHALOSE6PSYN-RXN | EC-2.4.1.15 | α,α-trehalose-phosphate synthase (UDP-forming) |
