| Basic Information | |
|---|---|
| Species | Brassica rapa |
| Cazyme ID | Bra008951 |
| Family | GT47 |
| Protein Properties | Length: 541 Molecular Weight: 62535.9 Isoelectric Point: 9.7394 |
| Chromosome | Chromosome/Scaffold: 10 Start: 14553268 End: 14555574 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 212 | 492 | 0 |
| QTLKVYVYSDGDRPIFHQPEAIMEGVYASEGWFMKLMESSHRFLTKDPTKAHLFYLAFSSRILQQKLYVRDSHSRRNLVKYLRDYIDLIVSRYPFWNRTR GFDHFFTACHDWAPAETRGPYMNCIRSLCNADVGLDFVVGKDVSLPETKISTAQNPNGNIGGNRPSKRTILAFFAGNMHGYVRPILLNHWSSSPEPDMKI FNRINHKSYIRFMKQSRFCVCAKGYEVNSPRVVESVLYGCVPVIISDNFVPPFLEVLDWESFAVFVPEKEIPNLRKILISI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 541 Download |
| MDQIRGFRFL GQAETCRVLL LMTLVVAFIL GLQYFELTPI STGTLGNGTV SGFIESNNIT 60 KGDENEMFLA PQEATSEFRP GNSTTEVLKS YEHKFLNNSP KAYGQSSGNE SASSHHPLQP 120 KIPHSNKKHE RSTKKPPLVV ISITQMNQMI VKRHSDPNNS LTPRWESNVD RELKDARNKI 180 KNAALVKKDN TLYAPLYHNL SIFKRSYELM EQTLKVYVYS DGDRPIFHQP EAIMEGVYAS 240 EGWFMKLMES SHRFLTKDPT KAHLFYLAFS SRILQQKLYV RDSHSRRNLV KYLRDYIDLI 300 VSRYPFWNRT RGFDHFFTAC HDWAPAETRG PYMNCIRSLC NADVGLDFVV GKDVSLPETK 360 ISTAQNPNGN IGGNRPSKRT ILAFFAGNMH GYVRPILLNH WSSSPEPDMK IFNRINHKSY 420 IRFMKQSRFC VCAKGYEVNS PRVVESVLYG CVPVIISDNF VPPFLEVLDW ESFAVFVPEK 480 EIPNLRKILI SIPLRRYVEM HKRVLKVQKH FMWHDGEPVR YDMFHMILHS VWYNRVFQTF 540 * 600 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 5.0e-66 | 214 | 492 | 299 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| DDBJ | BAC42362.1 | 0 | 1 | 540 | 1 | 546 | unknown protein [Arabidopsis thaliana] |
| RefSeq | NP_196722.1 | 0 | 1 | 540 | 1 | 546 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | NP_974766.1 | 0 | 1 | 438 | 1 | 444 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002309547.1 | 0 | 130 | 538 | 58 | 467 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002516500.1 | 0 | 136 | 539 | 51 | 453 | catalytic, putative [Ricinus communis] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
