y
Basic Information | |
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Species | Brassica rapa |
Cazyme ID | Bra009509 |
Family | GT47 |
Protein Properties | Length: 502 Molecular Weight: 56502 Isoelectric Point: 9.5961 |
Chromosome | Chromosome/Scaffold: 10 Start: 16969806 End: 16972173 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 170 | 451 | 0 |
EKQFKIFVYKEGEPPLFHDGPCKSIYSMEGNFIYEMETNTRFRTNNPEKAHAFYLPLSVVKMVRYVYERDSHDFSPIRKTVRDYIDLVGDKYPYWNRSIG ADHFILSCHDWGPEASFSHPHLGQNSIRALCNANTSERFKPRKDVSIPEINLLTGSLKGLVGGPSPSSRPILAFFAGGVHGPVRPVLLQHWENKDSDIRV HKYLPKGTSYSDMMRNSKFCICPSGYEVASPRIVEALYSGCVPVLINSGYVPPFSDVLNWASFSVIVSVEDIPNLKTILTSI |
Full Sequence |
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Protein Sequence Length: 502 Download |
MGDANVDGKC KMMSACSSAK LFLFMVPLVV VSGFLFVNPT SFLTSLSTNQ ISPPLPSYPS 60 LPPAAPSPSP PTSSLSTNAE SIQGNYNRTI QLNPTNIAST SSNVTSTASL KLMKKRVISN 120 LEKIEFELQK ARVAIKAASM NDPLDDPDYA PLGPMYWNAK AFHRSYLEME KQFKIFVYKE 180 GEPPLFHDGP CKSIYSMEGN FIYEMETNTR FRTNNPEKAH AFYLPLSVVK MVRYVYERDS 240 HDFSPIRKTV RDYIDLVGDK YPYWNRSIGA DHFILSCHDW GPEASFSHPH LGQNSIRALC 300 NANTSERFKP RKDVSIPEIN LLTGSLKGLV GGPSPSSRPI LAFFAGGVHG PVRPVLLQHW 360 ENKDSDIRVH KYLPKGTSYS DMMRNSKFCI CPSGYEVASP RIVEALYSGC VPVLINSGYV 420 PPFSDVLNWA SFSVIVSVED IPNLKTILTS ISPRQYLRMY RRVLKVRRHF EVNSPAKRFD 480 VFHMILHSIW VRRLNVRIRE V* 540 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 9.0e-67 | 169 | 451 | 305 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
DDBJ | BAB08605.1 | 0 | 96 | 501 | 3 | 408 | unnamed protein product [Arabidopsis thaliana] |
RefSeq | NP_001031828.1 | 0 | 68 | 501 | 85 | 518 | unknown protein [Arabidopsis thaliana] |
RefSeq | XP_002284018.1 | 0 | 169 | 500 | 1 | 332 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002326234.1 | 0 | 169 | 496 | 1 | 328 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002528630.1 | 0 | 73 | 500 | 147 | 567 | catalytic, putative [Ricinus communis] |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |