y
Basic Information | |
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Species | Brassica rapa |
Cazyme ID | Bra009863 |
Family | GT47 |
Protein Properties | Length: 680 Molecular Weight: 76102 Isoelectric Point: 9.8413 |
Chromosome | Chromosome/Scaffold: 06 Start: 17759064 End: 17761392 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 346 | 631 | 0 |
EKMLKVYVYKEGDKPIMHSPILRGIYASEGWFMKLIESNNNKFVTKDASKAHLFYLPFSSRMLEVTLYVQDSHSHRNLVQYLKDYIDFISVKYPFWNRTS GADHFLAACHDWAPSETRNVFAKSIRALCNSDVKEGFVFGKDTSLPETFVRDPKKPLSSIGGKSASQRPTLAFFAGKPDHGYLRPILLSYWGNNKDPDLK IFGKLPRTKGNKNYLQFMKTSKYCICAKGFEVNSPRVVEAIFYDCVPVIISDNFVPPFFEVLNWEAFALFVAEKDIPNLKKILMSV |
Full Sequence |
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Protein Sequence Length: 680 Download |
MRREFPGQWK VVESRRLLWL LGLTFALIVT FQYIELPNTI SSLFSSTKFP FSRNGDGEHK 60 SSRNLAPAMA PSFPQKNASL VDDSSGGGGD DEEVEVDKIF DSGGNATAPT VSPSQVKENA 120 TAPNVSPSQV KENATATNVS PSQVKESAPA PAVSPSQVKE SAPAPAVSPS QEKENATATN 180 VSPSQEKENA TAPVASAKPP AALPLVKENA TAPVASAKPP ASLPIPNPSP VKDNATSHVE 240 DKNSTKTNVP GASPPVVRFV PDVKEYSKTP DSRVMSISDM SKQLRRNRIS HNRLAKKPKW 300 VTKPDLELLQ AKYEIENAPI DDKDPLLYAP LYRNVSTFKR SYELMEKMLK VYVYKEGDKP 360 IMHSPILRGI YASEGWFMKL IESNNNKFVT KDASKAHLFY LPFSSRMLEV TLYVQDSHSH 420 RNLVQYLKDY IDFISVKYPF WNRTSGADHF LAACHDWAPS ETRNVFAKSI RALCNSDVKE 480 GFVFGKDTSL PETFVRDPKK PLSSIGGKSA SQRPTLAFFA GKPDHGYLRP ILLSYWGNNK 540 DPDLKIFGKL PRTKGNKNYL QFMKTSKYCI CAKGFEVNSP RVVEAIFYDC VPVIISDNFV 600 PPFFEVLNWE AFALFVAEKD IPNLKKILMS VSERRYRQMQ MRVKRVQKHF LWHVQPEKYD 660 MFHMILHSVW FNRVSQISV* 720 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
PRK07003 | PRK07003 | 2.0e-5 | 106 | 217 | 114 | + DNA polymerase III subunits gamma and tau; Validated | ||
PRK10856 | PRK10856 | 1.0e-5 | 137 | 217 | 86 | + cytoskeletal protein RodZ; Provisional | ||
pfam03016 | Exostosin | 7.0e-64 | 345 | 631 | 306 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_195005.1 | 0 | 252 | 677 | 172 | 593 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | NP_197954.1 | 0 | 1 | 679 | 1 | 654 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002281263.1 | 0 | 1 | 679 | 1 | 668 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002309547.1 | 0 | 255 | 677 | 49 | 468 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002324801.1 | 0 | 294 | 677 | 13 | 395 | predicted protein [Populus trichocarpa] |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |