| Basic Information | |
|---|---|
| Species | Brassica rapa |
| Cazyme ID | Bra010938 |
| Family | GT47 |
| Protein Properties | Length: 150 Molecular Weight: 17086.7 Isoelectric Point: 9.0941 |
| Chromosome | Chromosome/Scaffold: 08 Start: 17213200 End: 17213946 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 44 | 148 | 5.1e-33 |
| RLKVYVYDLPSKYNKKLLQKDPRCLTHMFAAEIFMHRFLLSSPVRTRNPDEADWFYTPIYPTCDLTPTGLPLPFKSPRMMRSAIQLISSNWPYWNRTEGA DHFFV | |||
| Full Sequence |
|---|
| Protein Sequence Length: 150 Download |
| MIRSSLSVIL LFLFLSASSA EHNARTERIS GSAGDVLEDN PVGRLKVYVY DLPSKYNKKL 60 LQKDPRCLTH MFAAEIFMHR FLLSSPVRTR NPDEADWFYT PIYPTCDLTP TGLPLPFKSP 120 RMMRSAIQLI SSNWPYWNRT EGADHFFVG* 180 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 5.0e-29 | 44 | 148 | 107 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAX33320.1 | 0 | 6 | 148 | 8 | 149 | secondary cell wall-related glycosyltransferase family 47 [Populus tremula x Populus tremuloides] |
| RefSeq | NP_174064.1 | 0 | 2 | 148 | 3 | 149 | GUT2; catalytic/ glucuronoxylan glucuronosyltransferase [Arabidopsis thaliana] |
| RefSeq | XP_002297880.1 | 0 | 6 | 148 | 8 | 149 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002304637.1 | 0 | 16 | 148 | 18 | 150 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002511079.1 | 0 | 6 | 148 | 9 | 154 | catalytic, putative [Ricinus communis] |
