| Basic Information | |
|---|---|
| Species | Brassica rapa |
| Cazyme ID | Bra010940 |
| Family | GT47 |
| Protein Properties | Length: 269 Molecular Weight: 30306.1 Isoelectric Point: 6.6718 |
| Chromosome | Chromosome/Scaffold: 08 Start: 17216892 End: 17218093 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 18 | 196 | 0 |
| EEKAIKRGILPLLERATLVQTFGQRNHVCLDQGSITIPPFAPPQKMQAHYIPPDIPRSIFVYFRGLFYDVNNDPEGGYYARGARAAVWENFKNNPLFDIS TDHPTTYYEDMQRSIFCLCPLGWAPWSPRLVEAVVFGCIPVIIADDIVLPFADAIPWEEIGVFVAEKDVPKLDTILTSI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 269 Download |
| MTLVPASIIR FNLDTKQEEK AIKRGILPLL ERATLVQTFG QRNHVCLDQG SITIPPFAPP 60 QKMQAHYIPP DIPRSIFVYF RGLFYDVNND PEGGYYARGA RAAVWENFKN NPLFDISTDH 120 PTTYYEDMQR SIFCLCPLGW APWSPRLVEA VVFGCIPVII ADDIVLPFAD AIPWEEIGVF 180 VAEKDVPKLD TILTSIPTEV ILRKQRLLAN PSMKQAMLFP QPAQPGDAFH QILNGLARKL 240 PHDRSIYLRE GEKVLNWTAG PVGDLKPW* 300 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 2.0e-38 | 3 | 196 | 200 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAX33320.1 | 0 | 17 | 268 | 161 | 412 | secondary cell wall-related glycosyltransferase family 47 [Populus tremula x Populus tremuloides] |
| RefSeq | NP_174064.1 | 0 | 17 | 268 | 161 | 412 | GUT2; catalytic/ glucuronoxylan glucuronosyltransferase [Arabidopsis thaliana] |
| RefSeq | XP_002297880.1 | 0 | 17 | 268 | 161 | 412 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002304637.1 | 0 | 17 | 268 | 162 | 413 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002512677.1 | 0 | 17 | 268 | 2 | 253 | catalytic, putative [Ricinus communis] |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| EX126260 | 244 | 26 | 269 | 0 |
| DW117895 | 253 | 17 | 269 | 0 |
| CO499349 | 253 | 17 | 269 | 0 |
| FQ432722 | 253 | 17 | 269 | 0 |
| ES900637 | 253 | 17 | 269 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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