| Basic Information | |
|---|---|
| Species | Brassica rapa |
| Cazyme ID | Bra011803 |
| Family | GT47 |
| Protein Properties | Length: 414 Molecular Weight: 47483.2 Isoelectric Point: 8.9711 |
| Chromosome | Chromosome/Scaffold: 01 Start: 436398 End: 437969 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 89 | 366 | 0 |
| EKRFKVYIYPDGDPNTFYQTPRKVTGKYASEGYFFKNIRESRFRTLDPEEADLFFVPVSPHKMRGKGTSYENMTVIVQTYVDGLIAKYPYWNRTLGADHF FVTCHDVGVRAFEGSPVMIKNTIRVVCSPSYNVGFIPHKDVALPQVLQPFALPAGGNDVENRTTLGFWAGHRNSKIRVVLARVWENDTELDISNNRINRA TGHLLYQKRFYRTKFCICPGGSQVNSARITDSIHYGCVPVILSDYYDLPFNDILDWRKFAVVLRERDVYDLKQILKNI | |||
| Full Sequence |
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| Protein Sequence Length: 414 Download |
| MTIVKPSQLS SSSSSSPLCS LKGSLLTLAV LTFLSLFYLS LDSLRTSPPS PIVVGANHLP 60 HTFAKEEDEN YSDVYHSPDS FRSNYAEMEK RFKVYIYPDG DPNTFYQTPR KVTGKYASEG 120 YFFKNIRESR FRTLDPEEAD LFFVPVSPHK MRGKGTSYEN MTVIVQTYVD GLIAKYPYWN 180 RTLGADHFFV TCHDVGVRAF EGSPVMIKNT IRVVCSPSYN VGFIPHKDVA LPQVLQPFAL 240 PAGGNDVENR TTLGFWAGHR NSKIRVVLAR VWENDTELDI SNNRINRATG HLLYQKRFYR 300 TKFCICPGGS QVNSARITDS IHYGCVPVIL SDYYDLPFND ILDWRKFAVV LRERDVYDLK 360 QILKNITQSE FVSLHNNLVK VQKHFQWNSP PVKFDAFHMI MYELWLRHHV IKY* 420 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 2.0e-62 | 88 | 366 | 298 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| DDBJ | BAH56870.1 | 0 | 1 | 383 | 1 | 395 | AT4G38040 [Arabidopsis thaliana] |
| RefSeq | NP_195517.1 | 0 | 1 | 413 | 1 | 425 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002266299.1 | 0 | 1 | 413 | 1 | 416 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002307304.1 | 0 | 18 | 413 | 1 | 406 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002522880.1 | 0 | 9 | 413 | 7 | 406 | catalytic, putative [Ricinus communis] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| FY454337 | 278 | 45 | 322 | 0 |
| EG459159 | 264 | 151 | 414 | 0 |
| EH770778 | 275 | 104 | 378 | 0 |
| JG847451 | 271 | 67 | 337 | 0 |
| GO268625 | 269 | 88 | 356 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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