Basic Information | |
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Species | Brassica rapa |
Cazyme ID | Bra011977 |
Family | GT47 |
Protein Properties | Length: 454 Molecular Weight: 51928.7 Isoelectric Point: 9.0744 |
Chromosome | Chromosome/Scaffold: 07 Start: 10816143 End: 10818161 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 97 | 397 | 0 |
NLKIYVYDLPSKFNTDWLANNRCSNHLFAAEVALHKALLSLEGDVRTEDPHEADFFFVPVYVSCNFSTVNGFPAIGHARSLIKEAIELVSAQYPFWNRTS GSDHVFTATHDFGSCFHTMEDRAIADGVPRILRNSIVLQTFGVTFKHPCQEVENVVIPPYISPVSLHKTQKNIPVTKERDIKVFFRGKMEFHPKNISGRF YSKRVRTEIWRSYSSDRRFYLQRQRFAGYQSEIARSVFCLCPLGWAPWSPRLVESVALGCVPVIIADGIRLPFPSAVRWPDISLTVAERDVGKLGEILEH V |
Full Sequence |
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Protein Sequence Length: 454 Download |
MITHKQRRTE KGLCFKHYFK WILCFSFTLY CLVSFLVDHD QEDLPLSPSS FSRPNTFLTN 60 PKTKFIASHA VFESKIHDHA LIFPPQRPNI RTDVFNNLKI YVYDLPSKFN TDWLANNRCS 120 NHLFAAEVAL HKALLSLEGD VRTEDPHEAD FFFVPVYVSC NFSTVNGFPA IGHARSLIKE 180 AIELVSAQYP FWNRTSGSDH VFTATHDFGS CFHTMEDRAI ADGVPRILRN SIVLQTFGVT 240 FKHPCQEVEN VVIPPYISPV SLHKTQKNIP VTKERDIKVF FRGKMEFHPK NISGRFYSKR 300 VRTEIWRSYS SDRRFYLQRQ RFAGYQSEIA RSVFCLCPLG WAPWSPRLVE SVALGCVPVI 360 IADGIRLPFP SAVRWPDISL TVAERDVGKL GEILEHVAET NLSVIQKNLE DPSVKRALLF 420 NVLPQEGDAT WQVLEALSKK LHRSAIRRSN AFL* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 9.0e-68 | 98 | 394 | 305 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAX33322.1 | 0 | 5 | 450 | 11 | 441 | secondary cell wall-related glycosyltransferase family 47 [Populus tremula x Populus tremuloides] |
GenBank | ABI64067.1 | 0 | 5 | 450 | 11 | 441 | glycosyltransferase GT47C [Populus tremula x Populus alba] |
RefSeq | NP_850113.2 | 0 | 1 | 453 | 1 | 448 | FRA8 (FRAGILE FIBER 8); glucuronosyltransferase/ transferase [Arabidopsis thaliana] |
RefSeq | XP_002314302.1 | 0 | 5 | 444 | 31 | 453 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002523710.1 | 0 | 4 | 444 | 28 | 452 | transferase, putative [Ricinus communis] |