| Basic Information | |
|---|---|
| Species | Brassica rapa |
| Cazyme ID | Bra016420 |
| Family | GT47 |
| Protein Properties | Length: 460 Molecular Weight: 52143.6 Isoelectric Point: 9.4804 |
| Chromosome | Chromosome/Scaffold: 08 Start: 18385596 End: 18387806 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GT47 | 86 | 382 | 0 |
| LSLKIYVYDENEIDGLKELMYGRDGSVKTAACLKGQWGSQIHKLLMESKFRTSKKEEADLFFVPAYVKCVRMLGGLNDKEINQTYVKVLSQMPYFRRSGG RDHIFVFPSGAGAHLFRSWSTFINRSFILTPEGDRTDKKDTTAFNTWKDIIIPGNVDDAMTKNGQPDVQPLPLSKRKYLANYLGRAQGKAGRLKLIDLSK QYPDKLECPDLKFSGTEKFGRTTYFEHLRNAKFCLAPRGESSWTLRFYESFFVECVPVLLSDHAELPFQNVIDYAQVSIKWPSSRIGPELLDYLASI | |||
| Full Sequence |
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| Protein Sequence Length: 460 Download |
| MASVSSSKPR NFGAYSYSAT PCTRTHQIGA LFLVVSTFFV TRILDQYFSE SNSVTPATDL 60 HRTSSSGITI DKGIPQWPER GYGSHLSLKI YVYDENEIDG LKELMYGRDG SVKTAACLKG 120 QWGSQIHKLL MESKFRTSKK EEADLFFVPA YVKCVRMLGG LNDKEINQTY VKVLSQMPYF 180 RRSGGRDHIF VFPSGAGAHL FRSWSTFINR SFILTPEGDR TDKKDTTAFN TWKDIIIPGN 240 VDDAMTKNGQ PDVQPLPLSK RKYLANYLGR AQGKAGRLKL IDLSKQYPDK LECPDLKFSG 300 TEKFGRTTYF EHLRNAKFCL APRGESSWTL RFYESFFVEC VPVLLSDHAE LPFQNVIDYA 360 QVSIKWPSSR IGPELLDYLA SIPDRDIEGM ISRGRKIRCL FVYGPDSAPC SAVKGILWEL 420 QRKARHFQQS TETFWLHNGS VVNRELVHFS SWRPPMPLP* |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 1.0e-41 | 88 | 382 | 309 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAF87908.1 | 0 | 1 | 459 | 1 | 414 | AC015447_18 Hypothetical protein [Arabidopsis thaliana] |
| GenBank | AAL75891.1 | 0 | 1 | 459 | 1 | 462 | At1g21480/F24J8_23 [Arabidopsis thaliana] |
| GenBank | AAM61682.1 | 0 | 1 | 459 | 1 | 462 | unknown [Arabidopsis thaliana] |
| RefSeq | NP_564141.1 | 0 | 1 | 459 | 1 | 462 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | NP_973879.1 | 0 | 1 | 382 | 1 | 385 | exostosin family protein [Arabidopsis thaliana] |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| BX841155 | 335 | 1 | 332 | 0 |
| CX668832 | 291 | 146 | 436 | 0 |
| EX093096 | 287 | 1 | 284 | 0 |
| FE707914 | 279 | 126 | 404 | 0 |
| CD825121 | 244 | 154 | 397 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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| Phylogeny |
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