| Basic Information | |
|---|---|
| Species | Brassica rapa |
| Cazyme ID | Bra022874 |
| Family | GT47 |
| Protein Properties | Length: 788 Molecular Weight: 89088.5 Isoelectric Point: 8.825 |
| Chromosome | Chromosome/Scaffold: 03 Start: 7515068 End: 7524493 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 65 | 415 | 0 |
| CLGRYIYIHKLPSKFNTDILQDCESITRPKDKISMCKYLDNSGFGPRIGDAVSIDSKYSPSWHATNQFMLEVIFHEKMKRYECLTRNSSLASAFYIPYYA GLDFRRNLRRRNVAERDAAGKEMVEWLKKQPQWKGMSGKDHFLVTGRISRDFRRNPDNNSLWGTNLMLLPESQNLSFLTIERSPTSHNEFAIPYPTYFHP TSTVEIRQWQDKIKLTNRTVLFSFAGAERPSRSHNGLVRTQVIQQCKSSSKTCRFLDCDVKANGCDDPMSLMKLFESSVFCLQPPGDSLTRRSVFDSILA GCIPVFFNQGSAYKQYVWHLPNNDGEYSVYIPVKELRTGGKSKIEEILQGI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 788 Download |
| MKNNNSSSSI KNQPCNKKPT ILLLLLSLLT TSLLILRLSQ NKTILITTTT TSDSDHHHRH 60 RHDSCLGRYI YIHKLPSKFN TDILQDCESI TRPKDKISMC KYLDNSGFGP RIGDAVSIDS 120 KYSPSWHATN QFMLEVIFHE KMKRYECLTR NSSLASAFYI PYYAGLDFRR NLRRRNVAER 180 DAAGKEMVEW LKKQPQWKGM SGKDHFLVTG RISRDFRRNP DNNSLWGTNL MLLPESQNLS 240 FLTIERSPTS HNEFAIPYPT YFHPTSTVEI RQWQDKIKLT NRTVLFSFAG AERPSRSHNG 300 LVRTQVIQQC KSSSKTCRFL DCDVKANGCD DPMSLMKLFE SSVFCLQPPG DSLTRRSVFD 360 SILAGCIPVF FNQGSAYKQY VWHLPNNDGE YSVYIPVKEL RTGGKSKIEE ILQGIPNEKV 420 IDMRENVIRL VPNIVYTKPN RYKPDRETFE DAFDVAVKGV IKRIEEKRRE IQDFMKLNNV 480 KMLNILIKSK MKGRRDFCSG FPLRLYGQFL EMLVEKVQNS IVSPNNSTLP LTERILEEED 540 WLDDGNDFGD VDGNDFGEED IDLMEEDDLL GEELRIENEK HLQIDDSGIE RADGGATLEI 600 TDGSGLGKVV ESTVDAKNKT PTKGASSSSD RVSGSSASMK KKRGSRSPSA FGVSLRQRLL 660 VVAVVTPSAN AIRKSVVLGG KSDVPNVQTN MEVQELGRYC VEQFNLHEQS GKGNVASSID 720 RAVLNPLTFS RVVSAQQQVV AGLKYYLRIE VTQPDRTSRM FDSVVVVQPW LHSKTLLGFT 780 PVATPIY* 840 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 2.0e-61 | 65 | 415 | 362 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004869 | cysteine-type endopeptidase inhibitor activity |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAD15405.1 | 0 | 1 | 469 | 9 | 481 | hypothetical protein [Arabidopsis thaliana] |
| RefSeq | NP_180759.2 | 0 | 1 | 469 | 1 | 473 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002280815.1 | 0 | 63 | 473 | 91 | 489 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002518609.1 | 0 | 31 | 473 | 40 | 472 | Xyloglucan galactosyltransferase KATAMARI1, putative [Ricinus communis] |
| RefSeq | XP_002532518.1 | 0 | 63 | 465 | 100 | 495 | Xyloglucan galactosyltransferase KATAMARI1, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3ima_D | 0.000000000002 | 677 | 782 | 2 | 91 | B Chain B, Complex Strcuture Of Tarocystatin And Papain |
| PDB | 3ima_B | 0.000000000002 | 677 | 782 | 2 | 91 | B Chain B, Complex Strcuture Of Tarocystatin And Papain |
| PDB | 1eqk_A | 0.0000002 | 677 | 782 | 8 | 96 | A Chain A, Solution Structure Of Oryzacystatin-I, A Cysteine Proteinase Inhibitor Of The Rice, Oryza Sativa L. Japonica |
| PDB | 2l4v_A | 0.000003 | 673 | 780 | 38 | 130 | A Chain A, Three Dimensional Structure Of Pineapple Cystatin |
| PDB | 3ul6_B | 0.0009 | 673 | 783 | 41 | 137 | A Chain A, Three Dimensional Structure Of Pineapple Cystatin |
