| Basic Information | |
|---|---|
| Species | Brassica rapa |
| Cazyme ID | Bra023001 |
| Family | GT47 |
| Protein Properties | Length: 440 Molecular Weight: 49734 Isoelectric Point: 8.1264 |
| Chromosome | Chromosome/Scaffold: 03 Start: 8165027 End: 8166643 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 53 | 363 | 0 |
| PKVKVYMYDLPNRFTHGIIEQHAIVRGGIKDDVTALKYPGHQHMHEWYLFSDLNRPETDRPGSPITRVSDPADADLFYVPVFSSLSLIVNAGRPVDPGSG YSDEKMQEELVDWLESQEWWRRNKGRDHVIPAGDPNALYRILDRVKNAVLLVADFGRLRPDQGSFVKDVVIPYSHRVNLFTGEIGVESRNTLLFFMGNRY RKDGGKVRDLLFQVLEKEEDVTIKHGTQSRENRRAATKGMHTSKFCLNPAGDTPSACRLFDSIVSLCVPVIVSDSIELPFEDVIDYRKFSIFVEAGVALE PGFLVGMLRKI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 440 Download |
| MARKSSLLKR AAIAVVSVIA IYVILNASVS PSLPSSSDLI REEDEQPRAP IHPKVKVYMY 60 DLPNRFTHGI IEQHAIVRGG IKDDVTALKY PGHQHMHEWY LFSDLNRPET DRPGSPITRV 120 SDPADADLFY VPVFSSLSLI VNAGRPVDPG SGYSDEKMQE ELVDWLESQE WWRRNKGRDH 180 VIPAGDPNAL YRILDRVKNA VLLVADFGRL RPDQGSFVKD VVIPYSHRVN LFTGEIGVES 240 RNTLLFFMGN RYRKDGGKVR DLLFQVLEKE EDVTIKHGTQ SRENRRAATK GMHTSKFCLN 300 PAGDTPSACR LFDSIVSLCV PVIVSDSIEL PFEDVIDYRK FSIFVEAGVA LEPGFLVGML 360 RKIGTEKVLE YQREMKQVRR YFDYDNPNGA VKEIWRQVSQ KLPLIKLMSN REKRLVLRNS 420 TEPDCSCLCT NQTGLVTSV* 480 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 8.0e-80 | 51 | 363 | 324 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAC61825.1 | 0 | 1 | 376 | 1 | 384 | unknown protein [Arabidopsis thaliana] |
| RefSeq | NP_199306.1 | 0 | 9 | 439 | 14 | 443 | ARAD2 (ARABINAN DEFICIENT 2); catalytic [Arabidopsis thaliana] |
| RefSeq | NP_850241.1 | 0 | 1 | 439 | 1 | 447 | ARAD1 (ARABINAN DEFICIENT 1); catalytic/ transferase, transferring glycosyl groups [Arabidopsis thaliana] |
| RefSeq | XP_002322391.1 | 0 | 1 | 439 | 1 | 457 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002523645.1 | 0 | 1 | 439 | 1 | 452 | catalytic, putative [Ricinus communis] |
