| Basic Information | |
|---|---|
| Species | Brassica rapa |
| Cazyme ID | Bra023587 |
| Family | GT47 |
| Protein Properties | Length: 537 Molecular Weight: 61128.3 Isoelectric Point: 9.5625 |
| Chromosome | Chromosome/Scaffold: 02 Start: 4077683 End: 4080184 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 142 | 451 | 0 |
| VKVYVYEMPKKFTFDLLWLFRNTYKETSNATSNGSPVHRLIEQHSVDYWLWADLISPESERRLKSVVRVHQQHEADFFYVPFFTTISFFLLEKQQCKALY REAVKWVTDQPAWKRSEGRDHIFPIHHPWSFKTVRKFVKNAIWLLPDMDSTGNWYKPGQVSLEKDLILPYVPNVDRCDDKCLSESAPKRTTLLFFRGRLK RNAGGKIRAKLGAELSGVKDVIIIEGTAGEGGKIAAQVGMRRSLFCLCPAGDTPSSARLFDAIVSGCIPVIVSDELELPFEGILDYKKVAVIVSSSDAIQ PGWLVNHLRS | |||
| Full Sequence |
|---|
| Protein Sequence Length: 537 Download |
| MNSLVVFFVG RVTEVSNRTR IEESDLAMVG NQRHHTPHRP RSKTLIFTLL LFSISLLVIL 60 YTFSSSSRPS ISNPNKSDRT ETSFVASLEQ FLIHKAPKLS IRDDTVHGES DDDDLKKLDE 120 KVFERENRLL IEDPVYPIGF PVKVYVYEMP KKFTFDLLWL FRNTYKETSN ATSNGSPVHR 180 LIEQHSVDYW LWADLISPES ERRLKSVVRV HQQHEADFFY VPFFTTISFF LLEKQQCKAL 240 YREAVKWVTD QPAWKRSEGR DHIFPIHHPW SFKTVRKFVK NAIWLLPDMD STGNWYKPGQ 300 VSLEKDLILP YVPNVDRCDD KCLSESAPKR TTLLFFRGRL KRNAGGKIRA KLGAELSGVK 360 DVIIIEGTAG EGGKIAAQVG MRRSLFCLCP AGDTPSSARL FDAIVSGCIP VIVSDELELP 420 FEGILDYKKV AVIVSSSDAI QPGWLVNHLR SFVPSQVKKF QSSLAQYSRH FVYSSPAQPL 480 GPEDLTWRMM AGKLVNIKLH TRRSLRVVEG SRSICRCDCW RRNSTTASNS LSPLLS* 540 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 4.0e-66 | 141 | 452 | 320 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI20132.1 | 0 | 149 | 525 | 1 | 377 | unnamed protein product [Vitis vinifera] |
| RefSeq | NP_197191.1 | 0 | 28 | 521 | 1 | 497 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002285599.1 | 0 | 81 | 525 | 63 | 511 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002325382.1 | 0 | 64 | 526 | 42 | 502 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002520033.1 | 0 | 73 | 525 | 49 | 502 | catalytic, putative [Ricinus communis] |
