| Basic Information | |
|---|---|
| Species | Brassica rapa |
| Cazyme ID | Bra028047 |
| Family | GT47 |
| Protein Properties | Length: 431 Molecular Weight: 48576.5 Isoelectric Point: 7.553 |
| Chromosome | Chromosome/Scaffold: 09 Start: 19037844 End: 19039425 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 47 | 354 | 0 |
| TGINVFVAELPRSLNYGLLDKYWSSPPDSRIPSDPDHPTRKPNPPKPGKYPENPLIKQYSAEYWMMGDLETPPEKRIGSFAKRVFSESEADVVFVPFFAT LSAEMELGNGKGSFRKRSGNEDYQRQRQVVDFLNKTQAWKRSGGRDHVFVLTDPVAMWHVRHEIALSILLVVDFGGWFRLDSKSSSFPERIEHTQVSVIK DGGLIREKLWDLLVDEHDIVMEEGFPNATGREQSIRGMRNSEFCLHPAGDTPTSCRLFDAIQSLCIPVIVSDNIELPFEGILDYSEFSVFVSVSDALTPK WLANHLRS | |||
| Full Sequence |
|---|
| Protein Sequence Length: 431 Download |
| MAVARPLCSH SCLFLAFSLV SIVSLLFFSN SLLSDPNLRI SRGTVETGIN VFVAELPRSL 60 NYGLLDKYWS SPPDSRIPSD PDHPTRKPNP PKPGKYPENP LIKQYSAEYW MMGDLETPPE 120 KRIGSFAKRV FSESEADVVF VPFFATLSAE MELGNGKGSF RKRSGNEDYQ RQRQVVDFLN 180 KTQAWKRSGG RDHVFVLTDP VAMWHVRHEI ALSILLVVDF GGWFRLDSKS SSFPERIEHT 240 QVSVIKDGGL IREKLWDLLV DEHDIVMEEG FPNATGREQS IRGMRNSEFC LHPAGDTPTS 300 CRLFDAIQSL CIPVIVSDNI ELPFEGILDY SEFSVFVSVS DALTPKWLAN HLRSFSERDK 360 ESFRSRMAKV QSVFVYDNGR ADGIGPIQPD GAVNHIWKKV QQKVPMVKEA VIRERRKPVG 420 TSVPLRCQCI * 480 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 2.0e-49 | 83 | 355 | 305 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | NP_564443.1 | 0 | 1 | 430 | 8 | 477 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002270238.1 | 0 | 7 | 429 | 16 | 439 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002325567.1 | 0 | 8 | 429 | 13 | 475 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002327326.1 | 0 | 23 | 429 | 3 | 448 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002533317.1 | 0 | 33 | 429 | 39 | 477 | catalytic, putative [Ricinus communis] |
