| Basic Information | |
|---|---|
| Species | Brassica rapa |
| Cazyme ID | Bra028388 |
| Family | GT47 |
| Protein Properties | Length: 700 Molecular Weight: 81508.6 Isoelectric Point: 8.7234 |
| Chromosome | Chromosome/Scaffold: 02 Start: 12173 End: 14827 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 268 | 607 | 0 |
| CRGKYVYMHDVPSLFNEELLKNCWTLSRWTDMCELTSNFGLGPRLPNMEGVSGWFATNQFTLEVIFHNRMKQYKCLTKDSSLASAVYVPYYPGLDLMRFL WGPFPFMRDAAALDLMKWLRERPEWKRMDGRDHFMVAGRTTWDFMRTPENESDWGNRLMILPEIRNMTMLLIESSPWNYHGFAVPYPTYFHPSTNAEILQ WQNRMRRIKRRYLFSFVGAPRPNLGDSIRTEIMDQCKASRRKCKLLECVSGSQKCYKPDQIMKFFLSSTFCLQPPGDSYTRRSTFDSILAGCIPVFFHPG SAYAQYIWHLPKDIGKYSVFIPEKNVKEGKASIEKVLSRI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 700 Download |
| MAMEKSSSKY RTQFWYVAMV SFLLWLVLLY LFSPSATTVH THERLFRQEN VINLPINVPK 60 HVQESDQAVL PVDVPKHDQE PDQPVVVSDV DSNTLPANTS QEVQISEDAK VVTDLVEELE 120 KENIENEKKR ADSGLSGRTT RSRRGHREPR KARLEPEKKR VHHNDDDNER NVVNSDENHQ 180 SYDKELNFLE PKDDVGSKKD RVGKEMANDL SNNDIESDNT SETVSEPKTQ RHFTPNKTVS 240 VAKNRVTSRR NRPKVMVRPR ATRRNDPCRG KYVYMHDVPS LFNEELLKNC WTLSRWTDMC 300 ELTSNFGLGP RLPNMEGVSG WFATNQFTLE VIFHNRMKQY KCLTKDSSLA SAVYVPYYPG 360 LDLMRFLWGP FPFMRDAAAL DLMKWLRERP EWKRMDGRDH FMVAGRTTWD FMRTPENESD 420 WGNRLMILPE IRNMTMLLIE SSPWNYHGFA VPYPTYFHPS TNAEILQWQN RMRRIKRRYL 480 FSFVGAPRPN LGDSIRTEIM DQCKASRRKC KLLECVSGSQ KCYKPDQIMK FFLSSTFCLQ 540 PPGDSYTRRS TFDSILAGCI PVFFHPGSAY AQYIWHLPKD IGKYSVFIPE KNVKEGKASI 600 EKVLSRIPRG KVVAMREEVV KLIPRLMYFN PSGKRGDAGR FEDAFDVAVD GVLQRVEGLR 660 KRIEEGNEEI FEFPEQFSWK YNVFGNVEKH EWDSYFDRH* 720 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 2.0e-66 | 267 | 607 | 354 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CAN64889.1 | 0 | 8 | 679 | 14 | 710 | hypothetical protein [Vitis vinifera] |
| RefSeq | NP_180468.1 | 0 | 1 | 698 | 1 | 719 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002280815.1 | 0 | 265 | 698 | 90 | 523 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002301846.1 | 0 | 208 | 698 | 64 | 557 | glycosyltransferase, CAZy family GT47 [Populus trichocarpa] |
| RefSeq | XP_002313430.1 | 0 | 266 | 698 | 138 | 569 | glycosyltransferase, CAZy family GT47 [Populus trichocarpa] |
