| Basic Information | |
|---|---|
| Species | Brassica rapa |
| Cazyme ID | Bra031981 |
| Family | GT47 |
| Protein Properties | Length: 502 Molecular Weight: 57391.2 Isoelectric Point: 9.8607 |
| Chromosome | Chromosome/Scaffold: 02 Start: 26813116 End: 26814992 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 119 | 437 | 0 |
| RPLKVYMYDMSPEFHFGLLGWKPERNGVVWPDVRVNVPHHPGGLNLQHSVEYWLTLDLLFSELPEDSRTSRAAIRVKNYTEADVVFVPFFSSLSYNRFSK VTQKQKLSRDRELQDKLVKFVTAQKEWKISGGKDHVIMAHHPNSMSTARHKLYPAMFVVADFGRYSPRVANVDKDIVAPYKHLVPSYVNDTSGFDSRPVL LYFQGAIYRKAGGFVRQELYYLLKEEKDVHFSFGSVQNHGISKAGVGMRSSKFCLNIAGDTPSSNRLFDAIASHCIPVIISDDIELPYEDVLNYNEFCIF VRASDALKKGFLLGLVRSI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 502 Download |
| MKKSVSPVSC FRLPEMVERS NTRYHRMFIT RISMIFLLIS ILSVLSWFLI LSSTNPNRVL 60 DHISVSGPTD SPLIIIKNSE KSPQQNDAEL PNPKNSGAKT EEVVQTLSCN QKVSPPSPRP 120 LKVYMYDMSP EFHFGLLGWK PERNGVVWPD VRVNVPHHPG GLNLQHSVEY WLTLDLLFSE 180 LPEDSRTSRA AIRVKNYTEA DVVFVPFFSS LSYNRFSKVT QKQKLSRDRE LQDKLVKFVT 240 AQKEWKISGG KDHVIMAHHP NSMSTARHKL YPAMFVVADF GRYSPRVANV DKDIVAPYKH 300 LVPSYVNDTS GFDSRPVLLY FQGAIYRKAG GFVRQELYYL LKEEKDVHFS FGSVQNHGIS 360 KAGVGMRSSK FCLNIAGDTP SSNRLFDAIA SHCIPVIISD DIELPYEDVL NYNEFCIFVR 420 ASDALKKGFL LGLVRSIGRE EWNKMWGRLK EVERYFDLRF PAKDDDGDYG VQMIWKAVAR 480 KAPLVKMKVH RFQRFTRPFL I* 540 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 7.0e-53 | 117 | 437 | 331 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAX33321.1 | 0 | 108 | 497 | 114 | 490 | secondary cell wall-related glycosyltransferase family 47 [Populus tremula x Populus tremuloides] |
| RefSeq | NP_187015.1 | 0 | 16 | 499 | 1 | 499 | EDA5 (embryo sac development arrest 5); catalytic [Arabidopsis thaliana] |
| RefSeq | NP_190126.1 | 0 | 16 | 496 | 3 | 454 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002319201.1 | 0 | 29 | 496 | 15 | 450 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002530948.1 | 0 | 52 | 499 | 38 | 483 | catalytic, putative [Ricinus communis] |
