| Basic Information | |
|---|---|
| Species | Brassica rapa |
| Cazyme ID | Bra034000 |
| Family | GT47 |
| Protein Properties | Length: 444 Molecular Weight: 50930.1 Isoelectric Point: 6.8862 |
| Chromosome | Chromosome/Scaffold: 02 Start: 10333788 End: 10335302 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 56 | 376 | 0 |
| PLRVFMYDLPRKFNIAMMDPHISDVEPISAKNLPPWPQTSGIKRQHSVEYWLMASLLHNGEGEREAVRVFDPESADAFYVPFFSSLSFNTHGKNMTDPDT EFDRLLQVDLMEYLENSNYWQRSGGRDHVIPMTHPNAFRFLRQQVNASILIVADFGRYPKEMARLDKDVVSPYVHVVESFREDGVSVGVGDGDDDSTPDP FEARGTLLYFRGNTVRKAEGRIRLKLEKLLAGNSDVHYEKSVATTQNIKVSTEGMRSSKFCLHPAGDTPSSCRLFDAIVSHCIPVIISDKIELPFEDEID YSEFSVFYSVKEALEPGFILD | |||
| Full Sequence |
|---|
| Protein Sequence Length: 444 Download |
| MYGKTICIIV FFVFLIASYS IYMGTVDPTP YFTQLQSLPR GISSSPCNSS TISPQPLRVF 60 MYDLPRKFNI AMMDPHISDV EPISAKNLPP WPQTSGIKRQ HSVEYWLMAS LLHNGEGERE 120 AVRVFDPESA DAFYVPFFSS LSFNTHGKNM TDPDTEFDRL LQVDLMEYLE NSNYWQRSGG 180 RDHVIPMTHP NAFRFLRQQV NASILIVADF GRYPKEMARL DKDVVSPYVH VVESFREDGV 240 SVGVGDGDDD STPDPFEARG TLLYFRGNTV RKAEGRIRLK LEKLLAGNSD VHYEKSVATT 300 QNIKVSTEGM RSSKFCLHPA GDTPSSCRLF DAIVSHCIPV IISDKIELPF EDEIDYSEFS 360 VFYSVKEALE PGFILDNLRQ FPKEKWLKMW ANLKNVSHHF EFQYPPKRED AVNMLWRQVK 420 HKIPNVKLAV HRNRRLKVPD WWL* 480 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 2.0e-73 | 56 | 375 | 327 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAC18793.1 | 0 | 1 | 423 | 1 | 440 | End is cut off [Arabidopsis thaliana] |
| RefSeq | NP_176908.2 | 0 | 1 | 443 | 1 | 430 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002272591.1 | 0 | 38 | 442 | 37 | 426 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002311068.1 | 0 | 56 | 442 | 1 | 380 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002512333.1 | 0 | 1 | 442 | 1 | 431 | catalytic, putative [Ricinus communis] |
