y
Basic Information | |
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Species | Brassica rapa |
Cazyme ID | Bra034389 |
Family | GT47 |
Protein Properties | Length: 452 Molecular Weight: 51751.3 Isoelectric Point: 9.7143 |
Chromosome | Chromosome/Scaffold: 04 Start: 12284314 End: 12286102 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 95 | 395 | 0 |
NLKIYVYDLPSKFNKDWLANERCSNHLFAAEVALHKALLSLRGDVRTEDPYEADFFFVPVYVSCNFSTVNGFPAIGQARSLINEAIDLVSPQHPFWNRTS GSDHVFTATHDFGSCFHTMEDRAIADGVPRMLRNSIVLQTFGVTYKHPCQEVENVVIPPYISPEGLRKTQKNIPAAKERDIRVFFRGKMEIHPKNISGRF YSKRIRTEIWRSYGGDRRFYLQRQRFAGYQSEIARSVFCLCPLGWAPWSPRLVESVALGCVPVIIADGIRLPFPSAVRWPDISLTVAERDVGRLGDILKH V |
Full Sequence |
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Protein Sequence Length: 452 Download |
MITQKQRRTE KSLCFKHYYK WILCFSLTLY FVASFFVDHD QEDHPSSSLS PSNPLITNPK 60 PKPLPSRAMF ESKIHDQRHG FPLQRPNIRT DVFNNLKIYV YDLPSKFNKD WLANERCSNH 120 LFAAEVALHK ALLSLRGDVR TEDPYEADFF FVPVYVSCNF STVNGFPAIG QARSLINEAI 180 DLVSPQHPFW NRTSGSDHVF TATHDFGSCF HTMEDRAIAD GVPRMLRNSI VLQTFGVTYK 240 HPCQEVENVV IPPYISPEGL RKTQKNIPAA KERDIRVFFR GKMEIHPKNI SGRFYSKRIR 300 TEIWRSYGGD RRFYLQRQRF AGYQSEIARS VFCLCPLGWA PWSPRLVESV ALGCVPVIIA 360 DGIRLPFPSA VRWPDISLTV AERDVGRLGD ILKHVAATNL SDIQKNLEDP SVRRALLFNV 420 PPREGDATWQ VLEALSKKLN RSVRRKSNDV L* 480 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 1.0e-64 | 96 | 393 | 306 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAX33322.1 | 0 | 5 | 444 | 11 | 435 | secondary cell wall-related glycosyltransferase family 47 [Populus tremula x Populus tremuloides] |
GenBank | ABI64067.1 | 0 | 5 | 444 | 11 | 435 | glycosyltransferase GT47C [Populus tremula x Populus alba] |
RefSeq | NP_850113.2 | 0 | 1 | 451 | 1 | 448 | FRA8 (FRAGILE FIBER 8); glucuronosyltransferase/ transferase [Arabidopsis thaliana] |
RefSeq | XP_002314302.1 | 0 | 5 | 444 | 31 | 455 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002523710.1 | 0 | 4 | 444 | 28 | 454 | transferase, putative [Ricinus communis] |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |