| Basic Information | |
|---|---|
| Species | Brassica rapa |
| Cazyme ID | Bra034534 |
| Family | GT47 |
| Protein Properties | Length: 603 Molecular Weight: 68844.6 Isoelectric Point: 6.8319 |
| Chromosome | Chromosome/Scaffold: 08 Start: 12997384 End: 12999542 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 272 | 556 | 0 |
| ESKLKVYVYREGKRPVFHKPVLKGIYASEGWFMRQLKASKTFVTKNPRKAHLFYLPFSSKMLEESLYVPGSHSDKNLVKFLKNYLDMISSKYHFWNKTGG SDHFLVACHDWAPSETRQYMANCIRALCNSDVSEGFVFGKDVALPETTILVPRRPLRALGGKPISQRHILAFFAGGMHGYLRPLLLQTWGGNRDPDMKIF SEIPKSKGKNKSYMEFMKSSKYCICPKGHEVNSPRVVEALFYECVPVIISDNFVPPFFEVINWESFAVFVLEKDIPDLKNILLSI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 603 Download |
| MKLLRFAGVV FIFILAFQFV NIHYYGGDIL SLSSQDEFPV SIHGSTEPIR PLSGPERLNV 60 SSSISAEVSE GERTGLGEDY VISSDANVSV QSHDAKDKET LDLLLETRSS MNGSDADIVN 120 ENNRNVEILE SDDFVEDAKD KDALDSLLET RSSSSNGSYG DVVEDAEIVN ENNRNVETLE 180 TRSDDNLSPE VKRVMNVSVS GVVSISEMMS LLHQSRTTHV SLKMKRPSAV DQELLYARTQ 240 IENSPKVEND PLLHGPLYWN LSMFKRSYEL MESKLKVYVY REGKRPVFHK PVLKGIYASE 300 GWFMRQLKAS KTFVTKNPRK AHLFYLPFSS KMLEESLYVP GSHSDKNLVK FLKNYLDMIS 360 SKYHFWNKTG GSDHFLVACH DWAPSETRQY MANCIRALCN SDVSEGFVFG KDVALPETTI 420 LVPRRPLRAL GGKPISQRHI LAFFAGGMHG YLRPLLLQTW GGNRDPDMKI FSEIPKSKGK 480 NKSYMEFMKS SKYCICPKGH EVNSPRVVEA LFYECVPVII SDNFVPPFFE VINWESFAVF 540 VLEKDIPDLK NILLSISEER YREMQMRVKM VQKHFLWHSK PERFDIFHMI LHSIWYNRVF 600 QT* 660 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 5.0e-77 | 271 | 556 | 306 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | NP_195005.1 | 0 | 1 | 601 | 29 | 592 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | NP_197954.1 | 0 | 189 | 601 | 236 | 651 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002281263.1 | 0 | 164 | 601 | 243 | 665 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002309547.1 | 0 | 140 | 601 | 22 | 467 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002324801.1 | 0 | 208 | 602 | 1 | 395 | predicted protein [Populus trichocarpa] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
