| Basic Information | |
|---|---|
| Species | Brassica rapa |
| Cazyme ID | Bra035655 |
| Family | GT47 |
| Protein Properties | Length: 664 Molecular Weight: 77323.8 Isoelectric Point: 9.599 |
| Chromosome | Chromosome/Scaffold: 04 Start: 13055267 End: 13057907 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 232 | 571 | 0 |
| CRGKYVYMHDVPSLFNEELLKNCWTLSRWTDMCELTSNFGLGPPLPNMEGVSGWFATNQFTLEVIFHNRMKQYKCLTKDSSLASAVYVPYYPGLDLMRFL WGPFPSMRDAAALDLMKWLRERQEWKRMDGRDHFMVAGRTTWDFMRTPGNESDWGNRLMILPEIRNMTMLLIESSPWNYHGFAVPYPTYFHPSTNAEILQ WQSRMRRIKRRYLFSFVGAPRPNLGDSIRSEIMDQCKASRRKCKLLECVSGSQKCYKPDQIMKFFLSSTFCLQPPGDSYTRRSTFDSILAGCIPVFFHPG SAYAQYIWHLPKDIGKYSVFLPGKNVKEGKASIERVLSRI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 664 Download |
| MAMDKSSSKY RTYFWYVAMV SFLLWLVLLY LFNSSVKTVH NHERLFRQEN VIDLPVHVSQ 60 QNHESDQAVV SNVDNITVPV TGNGSSQEVQ ISEDAKVVSD LVEELEKEDV ENVKKRGDTA 120 WSRRSTRSRG RHRESRRTRS SDKRMVRPNN DDENNVDNSD ENHQSLDKEP NFFEPRNDVT 180 SKKERVDDNN VVESKQKTSN NNTSKVNSRI SAKRNRPKVV VRPRVTRRND PCRGKYVYMH 240 DVPSLFNEEL LKNCWTLSRW TDMCELTSNF GLGPPLPNME GVSGWFATNQ FTLEVIFHNR 300 MKQYKCLTKD SSLASAVYVP YYPGLDLMRF LWGPFPSMRD AAALDLMKWL RERQEWKRMD 360 GRDHFMVAGR TTWDFMRTPG NESDWGNRLM ILPEIRNMTM LLIESSPWNY HGFAVPYPTY 420 FHPSTNAEIL QWQSRMRRIK RRYLFSFVGA PRPNLGDSIR SEIMDQCKAS RRKCKLLECV 480 SGSQKCYKPD QIMKFFLSST FCLQPPGDSY TRRSTFDSIL AGCIPVFFHP GSAYAQYIWH 540 LPKDIGKYSV FLPGKNVKEG KASIERVLSR IPKAKVVAMR EEVIKLIPRL MYFNPSGKRG 600 DAGRFEDAFD VAVEGVLGRV EGLRKRIEEG NEEIFDFPER FSWKYNVFGN VEKHEWDSYF 660 DRR* 720 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 1.0e-63 | 231 | 571 | 354 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ACY08857.1 | 0 | 228 | 662 | 153 | 590 | xyloglucan galactosyltransferase [Eucalyptus grandis] |
| EMBL | CAN64889.1 | 0 | 9 | 643 | 15 | 710 | hypothetical protein [Vitis vinifera] |
| RefSeq | NP_180468.1 | 0 | 1 | 662 | 1 | 719 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002280815.1 | 0 | 229 | 662 | 90 | 523 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002313430.1 | 0 | 230 | 662 | 138 | 569 | glycosyltransferase, CAZy family GT47 [Populus trichocarpa] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3in5_B | 0.009 | 270 | 431 | 128 | 263 | A Chain A, Unusual Structural Features In The Parallel Beta-Helix In Pectate Lyases |
| PDB | 3in5_A | 0.009 | 270 | 431 | 128 | 263 | A Chain A, Unusual Structural Features In The Parallel Beta-Helix In Pectate Lyases |
| PDB | 2w7p_B | 0.009 | 270 | 431 | 128 | 263 | A Chain A, Unusual Structural Features In The Parallel Beta-Helix In Pectate Lyases |
| PDB | 2w7p_A | 0.009 | 270 | 431 | 128 | 263 | A Chain A, Unusual Structural Features In The Parallel Beta-Helix In Pectate Lyases |
| PDB | 2w7o_B | 0.009 | 270 | 431 | 128 | 263 | A Chain A, Unusual Structural Features In The Parallel Beta-Helix In Pectate Lyases |
