| Basic Information | |
|---|---|
| Species | Brassica rapa |
| Cazyme ID | Bra038505 |
| Family | GT47 |
| Protein Properties | Length: 547 Molecular Weight: 63532.8 Isoelectric Point: 10.152 |
| Chromosome | Chromosome/Scaffold: 01 Start: 10791934 End: 10794024 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 202 | 487 | 0 |
| LKVYIYPDGEKPIFHQPHLNGIYASEGWFMKLMESNTQFVTKNPEKAHLFYMPYSVKQLQHAIFVPGSHNIKPLSIFIRDYVNMLSIKYPFWNRTHGSDH FLVACHDWGPYTVSEHPELRQNTIKALCNADLSDGIFVPGRDVSLPETSIRNAGRPLRNIGNGNRVSQRPILAFFAGNLHGRVRPQLLKHWRNKDDDMKI YGPLPHNVARKMTYVQHMKSSKYCLCPMGYEVNSPRIVEAIYYECVPVIIADNFVLPFSEVLDWSAFSVVVPEKDIPRIKEILLEI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 547 Download |
| MVTMKSPLRI FIEVSMKELI RSFRRQRIRW RNAFLLGSIM TTIVILLHTP TFSIFSDDEE 60 TESSSSPIYL NGSLHLNIQI VSEAKVESFP SLTTTPVVKM NSSSEIKRVD EETNLPRKRQ 120 KRKRRKKTKD DLILTDPPPA PRHILSSSER RALSLPPKEA LAFAKLEIQR APEVVNDTEL 180 FAPVFRNLSI FKRSYELMEL ILKVYIYPDG EKPIFHQPHL NGIYASEGWF MKLMESNTQF 240 VTKNPEKAHL FYMPYSVKQL QHAIFVPGSH NIKPLSIFIR DYVNMLSIKY PFWNRTHGSD 300 HFLVACHDWG PYTVSEHPEL RQNTIKALCN ADLSDGIFVP GRDVSLPETS IRNAGRPLRN 360 IGNGNRVSQR PILAFFAGNL HGRVRPQLLK HWRNKDDDMK IYGPLPHNVA RKMTYVQHMK 420 SSKYCLCPMG YEVNSPRIVE AIYYECVPVI IADNFVLPFS EVLDWSAFSV VVPEKDIPRI 480 KEILLEIPMR RYLKMQSNVK MVQKHFLWSP KPRRYDVFHM ILHSIWFNLL HHNQTSTHVP 540 SFRQHP* 600 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 5.0e-70 | 202 | 487 | 302 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CAB10449.1 | 0 | 20 | 541 | 508 | 1023 | limonene cyclase like protein [Arabidopsis thaliana] |
| EMBL | CBI23466.1 | 0 | 18 | 538 | 6 | 538 | unnamed protein product [Vitis vinifera] |
| RefSeq | NP_567512.2 | 0 | 1 | 541 | 1 | 541 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002269459.1 | 0 | 18 | 537 | 6 | 537 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002530666.1 | 0 | 66 | 534 | 54 | 524 | catalytic, putative [Ricinus communis] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
