y
Basic Information | |
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Species | Brassica rapa |
Cazyme ID | Bra038960 |
Family | GT47 |
Protein Properties | Length: 513 Molecular Weight: 59202.8 Isoelectric Point: 5.0151 |
Chromosome | Chromosome/Scaffold: 08 Start: 8596466 End: 8598004 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 86 | 430 | 0 |
SCSGRYIYLHDLPSRFNSDLLASCSLITRGTENNICPYLENFGFGPEIQDPDNILLKQSWFVTNQFMLEVIFHNKMKKYTCLTHNSSLASAVFIPFYAGI DMSRYLWGFNITVRDSSSHELMDWLVKQREWSRMSGRDHFFVAGRIAWDFRRQTDNESDWGSKLRFLPESQNMSMMSIESSSWNNDYAIPYPTCFHPSSV DEISEWQDRMRSQKRRYLFAFAGAPRPEYKDSVRGIIIDECLESDDQCYLLDCNYGKVNCDNPVNVMKVFRNSVFCLQPPGDSYTRRSMFDSILAGCIPV FFHPGTAYAQYKWHLPKNHNSYSVYLPVKDVKEWDIKIKERLLEI |
Full Sequence |
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Protein Sequence Length: 513 Download |
MEKPISVVTG KFRSSSSNNH SNVWFVVPLF ILLCFILLCF DYSALYITDT DEAASSFSDT 60 TQNSVSREST KDVNLSRFLD DPLPDSCSGR YIYLHDLPSR FNSDLLASCS LITRGTENNI 120 CPYLENFGFG PEIQDPDNIL LKQSWFVTNQ FMLEVIFHNK MKKYTCLTHN SSLASAVFIP 180 FYAGIDMSRY LWGFNITVRD SSSHELMDWL VKQREWSRMS GRDHFFVAGR IAWDFRRQTD 240 NESDWGSKLR FLPESQNMSM MSIESSSWNN DYAIPYPTCF HPSSVDEISE WQDRMRSQKR 300 RYLFAFAGAP RPEYKDSVRG IIIDECLESD DQCYLLDCNY GKVNCDNPVN VMKVFRNSVF 360 CLQPPGDSYT RRSMFDSILA GCIPVFFHPG TAYAQYKWHL PKNHNSYSVY LPVKDVKEWD 420 IKIKERLLEI SEERVVKLRE EVIKLIPSVV YANPSYGSEG SEDAFELAVK GMLEKIEEVR 480 EVMRQGKDGG EGFDDRDDYK YTFSPYEAQV LT* 540 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 1.0e-73 | 86 | 430 | 359 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CAB10178.1 | 0 | 1 | 512 | 1 | 482 | hypothetical protein [Arabidopsis thaliana] |
RefSeq | NP_193135.2 | 0 | 1 | 512 | 9 | 521 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002300146.1 | 0 | 1 | 510 | 7 | 519 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002321098.1 | 0 | 47 | 504 | 11 | 466 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002532518.1 | 0 | 1 | 506 | 1 | 524 | Xyloglucan galactosyltransferase KATAMARI1, putative [Ricinus communis] |