y
Basic Information | |
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Species | Brassica rapa |
Cazyme ID | Bra039028 |
Family | GT21 |
Protein Properties | Length: 522 Molecular Weight: 58671.1 Isoelectric Point: 8.8598 |
Chromosome | Chromosome/Scaffold: 07 Start: 661068 End: 664137 |
Description | Nucleotide-diphospho-sugar transferases superfamily protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT21 | 85 | 311 | 8.1e-34 |
PRVSVVMPLKGFGEHNLHNWRSQITSLYGGPLEFLFVLESTEDPAYHAVSRLLATHQDHVEAKVVIAGLATTCSQKIHNQLIGVEKMHKDTKYVLFLDDD VSLHPGTIGALTSEMEKNPEIFIQTGYPLDLPSGTLGSYCIYEYHMPCSMGFATGGTTFFLWGGCMMMHADDFRQDRYGVVSGLRDGGYSDDMTLAALAG AHKRLITSPPVAVFPHPLATDLSFGRY |
Full Sequence |
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Protein Sequence Length: 522 Download |
MSTTLDSMDS ILFSLSRAFC TPFAVFVQIQ GCVICLLLAL GWLMAAYVRN REIKRIKNSM 60 KAGNSLAFLY QDINELEHSR QAKLPRVSVV MPLKGFGEHN LHNWRSQITS LYGGPLEFLF 120 VLESTEDPAY HAVSRLLATH QDHVEAKVVI AGLATTCSQK IHNQLIGVEK MHKDTKYVLF 180 LDDDVSLHPG TIGALTSEME KNPEIFIQTG YPLDLPSGTL GSYCIYEYHM PCSMGFATGG 240 TTFFLWGGCM MMHADDFRQD RYGVVSGLRD GGYSDDMTLA ALAGAHKRLI TSPPVAVFPH 300 PLATDLSFGR YWNYLRKQTF VLESYISKVN WIMNKALFAV HCYLSWGFVA PYVMSVIHIT 360 SALRIYIKGY SQLEDATFAS SGMSLVILLA ICTFIELLAM WNLTRREVTL CNLLSPEAPR 420 LTLAPYHWGP IFIAMLVDNF LYPISAFRSH FSQSINWSGI RYHLRNGKVF KIERRNDMVP 480 AKTDLGGKHL YGKKGATHKA SFLSSLGRNL AHWRQPKKFD V* 540 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam13641 | Glyco_tranf_2_3 | 0.0002 | 85 | 318 | 239 | + Glycosyltransferase like family 2. Members of this family of prokaryotic proteins include putative glucosyltransferase, which are involved in bacterial capsule biosynthesis. | ||
cd04186 | GT_2_like_c | 0.0001 | 162 | 259 | 98 | + Subfamily of Glycosyltransferase Family GT2 of unknown function. GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families. | ||
cd02520 | Glucosylceramide_synthase | 2.0e-8 | 85 | 205 | 124 | + Glucosylceramide synthase catalyzes the first glycosylation step of glycosphingolipid synthesis. UDP-glucose:N-acylsphingosine D-glucosyltransferase (glucosylceramide synthase or ceramide glucosyltransferase) catalyzes the first glycosylation step of glycosphingolipid synthesis. Its product, glucosylceramide, serves as the core of more than 300 glycosphingolipids (GSL). GSLs are a group of membrane components that have the lipid portion embedded in the outer plasma membrane leaflet and the sugar chains extended to the outer environment. Several lines of evidence suggest the importance of GSLs in various cellular processes such as differentiation, adhesion, proliferation, and cell-cell recognition. In pathogenic fungus Cryptococcus neoformans, glucosylceramide serves as an antigen that elicits an antibody response in patients and it is essential for fungal growth in host extracellular environment. | ||
COG1215 | COG1215 | 1.0e-9 | 82 | 403 | 341 | + Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane] | ||
pfam13506 | Glyco_transf_21 | 4.0e-11 | 143 | 316 | 178 | + Glycosyl transferase family 21. This is a family of ceramide beta-glucosyltransferases - EC:2.4.1.80. |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAK73021.1 | 0 | 1 | 521 | 1 | 520 | AF367245_1 ceramide glucosyltransferase [Gossypium arboreum] |
GenBank | AAL11579.1 | 0 | 3 | 521 | 2 | 519 | AF424585_1 At2g19880/F6F22.9 [Arabidopsis thaliana] |
GenBank | ABK95617.1 | 0 | 6 | 521 | 3 | 517 | unknown [Populus trichocarpa] |
RefSeq | NP_565460.1 | 0 | 3 | 521 | 2 | 519 | ceramide glucosyltransferase, putative [Arabidopsis thaliana] |
RefSeq | XP_002514215.1 | 0 | 2 | 520 | 4 | 521 | ceramide glucosyltransferase, putative [Ricinus communis] |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
sphingolipid biosynthesis (plants) | RXN-7793 | EC-2.4.1.80 | ceramide glucosyltransferase |