| Basic Information | |
|---|---|
| Species | Brassica rapa |
| Cazyme ID | Bra040019 |
| Family | GT47 |
| Protein Properties | Length: 554 Molecular Weight: 64166.4 Isoelectric Point: 6.9685 |
| Chromosome | Chromosome/Scaffold: 01 Start: 27899146 End: 27902136 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 72 | 354 | 0 |
| EKMFKIYVYEEGDPPIFHYGLCKDIYSMEGLLLNFMENDVLTYRTRDPDKAHVYFLPFSVVMILHHLFDPVVRDKAVLERVIVDYVQIISEKYPYWNTSD GFDHFMLSCHDWGHRATWYVKKLFFNSIRVLCNANISEYFNPEKDAPFPEINLQTGEINNLTGGLDPMSRTTLAFFAGQSHGKIRPVLLNHWKEKDKDIL VYEDLPGELDYKEMMRKSRFCICPSGHEVASPRVPEAIYSGCVPVLISENYVLPFSDVLNWEKFSVSVSVKEIPELKRILMDI | |||
| Full Sequence |
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| Protein Sequence Length: 554 Download |
| MRKRNGSNPG SLSWKRDKKV EAELATARAL IREAQLNPNS TTSSPLRDED YVPHGEIYRN 60 PYAFHRSYLL MEKMFKIYVY EEGDPPIFHY GLCKDIYSME GLLLNFMEND VLTYRTRDPD 120 KAHVYFLPFS VVMILHHLFD PVVRDKAVLE RVIVDYVQII SEKYPYWNTS DGFDHFMLSC 180 HDWGHRATWY VKKLFFNSIR VLCNANISEY FNPEKDAPFP EINLQTGEIN NLTGGLDPMS 240 RTTLAFFAGQ SHGKIRPVLL NHWKEKDKDI LVYEDLPGEL DYKEMMRKSR FCICPSGHEV 300 ASPRVPEAIY SGCVPVLISE NYVLPFSDVL NWEKFSVSVS VKEIPELKRI LMDIPEDRYK 360 KLYEGVKQVQ RHILVNDPPK RYDQKILIRV TMTDDKARAK AMKTAVKFKG VSAVEIKGDH 420 RNQIEVTGVE VDMIGLTNTL RRKVACAELV SVNKVEPPKP EEDKKPEEKK PEEKKPDEAK 480 PEEKKPDEKK PEEEKQEPCH CHPPCHQPCH QQPWPYGYGM PSSYHHPCNP YGYNARDYIG 540 EPVYNHEPNC TIL* 600 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam00403 | HMA | 0.003 | 386 | 445 | 60 | + Heavy-metal-associated domain. | ||
| pfam03016 | Exostosin | 2.0e-67 | 71 | 354 | 302 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| GO:0030001 | metal ion transport |
| GO:0046872 | metal ion binding |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI28482.1 | 0 | 1 | 383 | 225 | 616 | unnamed protein product [Vitis vinifera] |
| RefSeq | NP_187419.1 | 0 | 2 | 383 | 70 | 451 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002264111.1 | 0 | 71 | 383 | 1 | 312 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002320537.1 | 0 | 10 | 383 | 4 | 375 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002524592.1 | 0 | 18 | 383 | 5 | 368 | catalytic, putative [Ricinus communis] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| FD546223 | 248 | 136 | 383 | 0 |
| EY930561 | 244 | 88 | 331 | 0 |
| GW895167 | 319 | 27 | 345 | 0 |
| GW864815 | 296 | 87 | 381 | 0 |
| FE523338 | 288 | 49 | 335 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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